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- W2091814672 abstract "Skin is the most voluminous organ of the body. It assumes several important physiological functions and represents also a “social interface” between an individual and other members of society. This is the main reason its age-dependent modifications are in the forefront of dermatological research and of the “anti-aging” cosmetic industry. Here we concentrate on some aspects only of skin aging, as far as the cellular and extracellular matrix components of skin are concerned. Most well studied mechanisms of skin aging can be situated at the postgenetic level, both epigenetic and post-translational mechanisms being involved. Some of these mechanisms will be reviewed as well as the capacity of fucose- and rhamnose-rich oligo- and polysaccharides (FROP and RROP) to counteract several of the mechanisms involved in skin aging. La peau est l’organe le plus volumineux du corps et assure plusieurs fonctions physiologiques importantes. Parmi ces fonctions, il y a le rôle de la peau comme interface entre l’individu et la société. C’est la raison essentielle de l’importance qu’a prise la recherche sur le vieillissement cutané au cours des dernières années, aussi bien en dermatologie qu’en dermocosmétologie. Dans cette revue, nous analyserons essentiellement les mécanismes postgénétiques, épigénétiques et post-traductionnels impliqués dans le vieillissement cutané. Nous décrirons aussi des expériences portant sur des oligo- et polysaccharides riches en fucose (FROP) ou en rhamnose (RROP), capables d’inhiber certains des mécanismes impliqués dans le vieillissement cutané." @default.
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- W2091814672 date "2009-06-01" @default.
- W2091814672 modified "2023-10-16" @default.
- W2091814672 title "Physiology of skin aging" @default.
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- W2091814672 doi "https://doi.org/10.1016/j.patbio.2008.09.007" @default.
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