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- W2091833426 abstract "Cardiac and thoracic aortic tissue were removed from 8-9 week old Dahl salt resistant (DR) and salt sensitive (DS) rats following 2 and 4 weeks of 8% NaCI diets. The tissue was used to determine the pool size and rate of [32P] Pi incorporation into phosphatidylinositol-4-5-bisphosphate (PIP2), phosphatidylinositol-4-phosphate (PIP) and phosphatidic acid (PA). The studies show no strain differences in the pool size of these phospholipids nor any changes in pool size as a consequence of the duration of exposure to the 8% NaCI diet. However, [32P] Pi incorporation into PIP2, PIP and PA was increased in the cardiac tissue isolated from both DR and DS rats exposed to 4 versus 2 weeks of 8% NaCI diet prior to sacrifice. The relative increase was comparable in both strains. Further, the extent of [32P] Pi incorporation into these phospholipids was also increased in the aorta of DR, but not DS, rats exposed to 8% NaCI diets for 4 versus 2 weeks. The present study defines a strain specific difference in aortic tissue response to prolonged 8% NaCI diet exposure." @default.
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- W2091833426 date "1987-01-01" @default.
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- W2091833426 title "Cardiovascular Tissue Phospholipid Metabolism in the Dahl Rat: Influence of Dietary Salt" @default.
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- W2091833426 doi "https://doi.org/10.3109/10641968709160041" @default.
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