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- W2091835413 abstract "Abstract— Release of malondialdehyde from microsomal phospholipids during incubation in vitro was studied in the brain cytoplasm and in the microsomes fortified by deproteinized cytosole. Linearity between the log of specific activity of peroxidation (malondialdehyde release) and the negative log of protein concentration was demonstrated. The boiling of microsomes significantly quenched the ability to produce malondialdehyde, while preincubation with phospholipase A completely abolished this ability. In general, aromatic and not aliphatic compounds inhibited the reaction. 1,1,1-Trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) was found to be a selective inhibitor of membrane peroxidative activity. The maximal inhibition is invariable. The data obtained revealed that brain and liver microsomal phospholipid peroxidation differ in some respects and the differences are of both quantitative and qualitative nature." @default.
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- W2091835413 date "1973-04-01" @default.
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- W2091835413 title "ENDOGENOUS MICROSOMAL PHOSPHOLIPID PEROXIDATION IN MOUSE BRAIN" @default.
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- W2091835413 doi "https://doi.org/10.1111/j.1471-4159.1973.tb00093.x" @default.
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