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• W2091906384 abstract "The spontaneously hypertensive rat (SHR) may model aspects of human attention deficit hyperactivity disorder (ADHD). For example, just as responses by children with ADHD tend to be variable, so too SHRs often respond more variably than do Wistar‐Kyoto (WKY) control rats. The present study asked whether behavioral variability in the SHR strain is influenced by rearing environment, a question related to hypotheses concerning the etiology of human ADHD. Some rats from each strain were reared in an enriched environment (housed socially), and others were reared in an impoverished environment (housed in isolation). Four groups—enriched SHR, impoverished SHR, enriched WKY, and impoverished WKY—were studied under two reinforcement contingencies, one in which reinforcement was independent of response variability and the other in which reinforcement depended upon high variability. The main finding was that rearing environment did not influence response variability (enriched and impoverished subjects responded similarly throughout). However, rearing environment affected body weight (enriched subjects weighed more than impoverished subjects) and response rate (impoverished subjects generally responded faster than enriched subjects). In addition, SHRs tended to respond variably throughout the experiment, whereas WKYs were more sensitive to the variability contingencies. Thus, behavioral variability was affected by genetic strain and by reinforcement contingency but not by the environment in which the subjects were reared." @default.
• W2091906384 created "2016-06-24" @default.
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• W2091906384 date "1996-01-01" @default.
• W2091906384 modified "2023-10-17" @default.
• W2091906384 title "BEHAVIORAL VARIABILITY IN SHR AND WKY RATS AS A FUNCTION OF REARING ENVIRONMENT AND REINFORCEMENT CONTINGENCY" @default.
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• W2091906384 doi "https://doi.org/10.1901/jeab.1996.65-129" @default.
• W2091906384 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1350067" @default.
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