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- W2091914316 abstract "Platelet regeneration time (PRT), based on assessment of platelet MDA-production before and after intake of acetylsalicylic acid (ASA), was determined using a sensitive and semi-automated method in 12 healthy volunteers and 28 patients with either prosthetic heart valves, aorto-iliac grafts or various forms of occlusive vascular disease. The results obtained confirm previous observations based on 51Cr-platelet survival times (PST) that platelet turnover is significantly enhanced in patients bearing prosthetic material and in a considerable proportion of patients with occlusive vascular disease. In 3 volunteers and in 4 out of 5 patients in whom PRT as well as PST were concomitantly determined, a reasonable agreement was found between turnover half-times obtained with the two methods. The validity of PRT-determination as an alternative to PST in cardiovascular patients is discussed." @default.
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- W2091914316 date "1979-01-01" @default.
- W2091914316 modified "2023-09-23" @default.
- W2091914316 title "Measurement of platelet regeneration time in cardiovascular patients" @default.
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- W2091914316 doi "https://doi.org/10.1016/0049-3848(79)90019-7" @default.
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