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• W2091964142 abstract "The purpose of this study was to investigate quantitatively the distribution of calcitonin gene-related peptide (CGRP)-positive neurons within the superior olivary complex (SOC) at various postnatal ages. In the lateral superior olive (LSO), most if not all, CGRP-positive cells correspond to the cholinergic portion of the lateral olivocochlear system which innervates the cochlea. Brains from 1-day old (P1) through juvenile (P30) hamsters were used. At all ages, CGRP-positive neurons were seen throughout the various nuclei of the SOC. There was a dramatic shift in the distribution of CGRP-positive neurons from being predominantly periolivary to being predominantly confined within the LSO. The number of CGRP-positive neurons clearly increased as a function of increasing age. At the earliest postnatal ages, the LSO contained few if any immunostained cells, whereas at later ages the LSO contained the majority (greater than 70%) of the immunostained cells. Assuming that these CGRP-positive cells within the LSO correspond to olivocochlear neurons, these data suggest that in hamsters the lateral olivocochlear system may be immature at birth up until the second postnatal week." @default.
• W2091964142 created "2016-06-24" @default.
• W2091964142 creator A5029526235 @default.
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• W2091964142 date "1993-11-01" @default.
• W2091964142 modified "2023-09-27" @default.
• W2091964142 title "Postnatal calcitonin gene-related peptide in the superior olivary complex" @default.
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• W2091964142 doi "https://doi.org/10.1016/0891-0618(93)90015-v" @default.
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