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- W2091978120 abstract "New fluorescein and rhodamine B-labeled antifilarial drug DEC analogues for use in drug localization studies with confocal microscopy have been prepared by a high-yield three-step synthesis. The resulting beta-amine-substituted DEC analogue has a single ethyl substituent which is beta-aminated to accommodate the fluorophore of either fluorescein isothiocyananate or rhodamine B. Confocal microscopy is used to show that the drug accumulates in the adult filarial worms in the pharynx, esophagus, and near the nerve ring of all adults, as well as in the uteri and vulva and the testes of the females and males." @default.
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- W2091978120 date "2007-11-01" @default.
- W2091978120 modified "2023-09-25" @default.
- W2091978120 title "Fluorescent Diethylcarbamazine Analogues: Sites of Accumulation inBrugia malayi" @default.
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- W2091978120 doi "https://doi.org/10.1021/bc0701040" @default.
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