FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091999009> ?p ?o ?g. }

• W2091999009 endingPage "155" @default.
• W2091999009 startingPage "148" @default.
• W2091999009 abstract "We used a DNA microarray to compare the gene expression profiles in liver among three groups of mice fed a diet containing 5% royal jelly (RJ), a diet containing 5% RJ stored at 40 degrees C for 7 d (40-7d RJ) or a control diet which provides the same total energy as RJ. Expression of 267 genes was increased or decreased by 1.8-fold or more in animals given the RJ diet for 14 d as compared with control diet, though serum total cholesterol, triglyceride, phospholipid, glucose, insulin and leptin levels were unaffected. Many genes involved in cell growth, signal transduction, energy metabolism and transcription regulation were responsive to the RJ diet. Among the 267 genes whose expression was altered by RJ, 60% showed no change or a reduced change in response to 40-7d RJ diet. The 40-7d RJ diet contained little 57-kDa protein, identified as a possible freshness marker of RJ. Furthermore, the RJ diet did not influence the gene expression of cytochrome P450 enzymes and detoxifying enzymes, whereas the 40-7d RJ diet increased the gene expression of glutathione S-transferase and glutathione peroxidase. Indeed, the RJ diet decreased the gene expression of cytochrome P450 4A14 (CYP4A14), which catalyzes peroxidation of endogenous lipids that is associated with nonalcoholic steatohepatitis and alcoholic liver disease, while the 40-7d RJ diet was not effective to decrease the gene expression of CYP4A14. The results indicate that the efficacy of RJ decreased and the toxicity of RJ increased during storage at high temperature. We suggest that application of DNA microarray technology to the biochemical evaluation of food safety may be effective for rapid and precise quality control." @default.
• W2091999009 created "2016-06-24" @default.
• W2091999009 creator A5022359679 @default.
• W2091999009 creator A5036846494 @default.
• W2091999009 creator A5037698866 @default.
• W2091999009 creator A5043097417 @default.
• W2091999009 creator A5047595725 @default.
• W2091999009 creator A5062841581 @default.
• W2091999009 creator A5072631091 @default.
• W2091999009 date "2005-01-01" @default.
• W2091999009 modified "2023-09-25" @default.
• W2091999009 title "Influence of Royal Jelly on Mouse Hepatic Gene Expression and Safety Assessment with a DNA Microarray" @default.
• W2091999009 cites W11470070 @default.
• W2091999009 cites W1515010604 @default.
• W2091999009 cites W1556472699 @default.
• W2091999009 cites W1866176581 @default.
• W2091999009 cites W1925380583 @default.
• W2091999009 cites W1940919815 @default.
• W2091999009 cites W1963533730 @default.
• W2091999009 cites W1970156673 @default.
• W2091999009 cites W1970588384 @default.
• W2091999009 cites W1973189365 @default.
• W2091999009 cites W1990015940 @default.
• W2091999009 cites W2013734796 @default.
• W2091999009 cites W2041732223 @default.
• W2091999009 cites W2047976786 @default.
• W2091999009 cites W2058223810 @default.
• W2091999009 cites W2072088094 @default.
• W2091999009 cites W2080435498 @default.
• W2091999009 cites W2090204807 @default.
• W2091999009 cites W2100837269 @default.
• W2091999009 cites W2145028184 @default.
• W2091999009 cites W2166478128 @default.
• W2091999009 cites W2169052484 @default.
• W2091999009 cites W2169624083 @default.
• W2091999009 cites W2334366410 @default.
• W2091999009 cites W2567623554 @default.
• W2091999009 cites W2741434670 @default.
• W2091999009 cites W3003998048 @default.
• W2091999009 cites W3201729753 @default.
• W2091999009 cites W773557302 @default.
• W2091999009 doi "https://doi.org/10.3177/jnsv.51.148" @default.
• W2091999009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16161764" @default.
• W2091999009 hasPublicationYear "2005" @default.
• W2091999009 type Work @default.
• W2091999009 sameAs 2091999009 @default.
• W2091999009 citedByCount "17" @default.
• W2091999009 countsByYear W20919990092012 @default.
• W2091999009 countsByYear W20919990092013 @default.
• W2091999009 countsByYear W20919990092015 @default.
• W2091999009 countsByYear W20919990092016 @default.
• W2091999009 countsByYear W20919990092018 @default.
• W2091999009 countsByYear W20919990092020 @default.
• W2091999009 countsByYear W20919990092022 @default.
• W2091999009 crossrefType "journal-article" @default.
• W2091999009 hasAuthorship W2091999009A5022359679 @default.
• W2091999009 hasAuthorship W2091999009A5036846494 @default.
• W2091999009 hasAuthorship W2091999009A5037698866 @default.
• W2091999009 hasAuthorship W2091999009A5043097417 @default.
• W2091999009 hasAuthorship W2091999009A5047595725 @default.
• W2091999009 hasAuthorship W2091999009A5062841581 @default.
• W2091999009 hasAuthorship W2091999009A5072631091 @default.
• W2091999009 hasBestOaLocation W20919990091 @default.
• W2091999009 hasConcept C104317684 @default.
• W2091999009 hasConcept C126322002 @default.
• W2091999009 hasConcept C134018914 @default.
• W2091999009 hasConcept C150194340 @default.
• W2091999009 hasConcept C181199279 @default.
• W2091999009 hasConcept C2778027074 @default.
• W2091999009 hasConcept C2778760513 @default.
• W2091999009 hasConcept C2778772119 @default.
• W2091999009 hasConcept C2779134260 @default.
• W2091999009 hasConcept C2779478299 @default.
• W2091999009 hasConcept C31903555 @default.
• W2091999009 hasConcept C4733338 @default.
• W2091999009 hasConcept C538909803 @default.
• W2091999009 hasConcept C55493867 @default.
• W2091999009 hasConcept C71924100 @default.
• W2091999009 hasConcept C86803240 @default.
• W2091999009 hasConceptScore W2091999009C104317684 @default.
• W2091999009 hasConceptScore W2091999009C126322002 @default.
• W2091999009 hasConceptScore W2091999009C134018914 @default.
• W2091999009 hasConceptScore W2091999009C150194340 @default.
• W2091999009 hasConceptScore W2091999009C181199279 @default.
• W2091999009 hasConceptScore W2091999009C2778027074 @default.
• W2091999009 hasConceptScore W2091999009C2778760513 @default.
• W2091999009 hasConceptScore W2091999009C2778772119 @default.
• W2091999009 hasConceptScore W2091999009C2779134260 @default.
• W2091999009 hasConceptScore W2091999009C2779478299 @default.
• W2091999009 hasConceptScore W2091999009C31903555 @default.
• W2091999009 hasConceptScore W2091999009C4733338 @default.
• W2091999009 hasConceptScore W2091999009C538909803 @default.
• W2091999009 hasConceptScore W2091999009C55493867 @default.
• W2091999009 hasConceptScore W2091999009C71924100 @default.
• W2091999009 hasConceptScore W2091999009C86803240 @default.
• W2091999009 hasIssue "3" @default.
• W2091999009 hasLocation W20919990091 @default.
• W2091999009 hasLocation W20919990092 @default.

• next