Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092014174> ?p ?o ?g. }
- W2092014174 endingPage "260" @default.
- W2092014174 startingPage "251" @default.
- W2092014174 abstract "The pathogenesis of multiple sclerosis (MS), a human demyelinating disease of the central nervous system (CNS), is currently unknown. It is widely thought that MS is an autoimmune disease which is supported by animal studies showing that myelin-specific CD4+ T cells can induce similar clinical disease in mice as observed in MS. However, the mechanism(s) of activation of these autoreactive CD4+ T cells are unknown. Although genetic susceptibility is important, other factors may be involved. Viral infections have long thought to be involved in the pathogenesis of MS although there exists little or no direct evidence implicating a role for a specific virus in MS pathogenesis. This review will discuss two models of virus-induced CNS autoimmunity, molecular mimicry and epitope spreading. These two mechanisms of activation of autoreactive T cells are presented in the context of MS." @default.
- W2092014174 created "2016-06-24" @default.
- W2092014174 creator A5033876610 @default.
- W2092014174 creator A5066868627 @default.
- W2092014174 creator A5068884058 @default.
- W2092014174 date "2002-10-01" @default.
- W2092014174 modified "2023-10-04" @default.
- W2092014174 title "Epitope spreading and molecular mimicry as triggers of autoimmunity in the Theiler's virus-induced demyelinating disease model of multiple sclerosis" @default.
- W2092014174 cites W1508020795 @default.
- W2092014174 cites W1526603781 @default.
- W2092014174 cites W1573240688 @default.
- W2092014174 cites W1595475267 @default.
- W2092014174 cites W1860214796 @default.
- W2092014174 cites W1983077792 @default.
- W2092014174 cites W1990840926 @default.
- W2092014174 cites W2001393467 @default.
- W2092014174 cites W2001764506 @default.
- W2092014174 cites W2010418081 @default.
- W2092014174 cites W2016333231 @default.
- W2092014174 cites W2018027744 @default.
- W2092014174 cites W2022649266 @default.
- W2092014174 cites W2027180135 @default.
- W2092014174 cites W2030562643 @default.
- W2092014174 cites W2031196287 @default.
- W2092014174 cites W2032582850 @default.
- W2092014174 cites W2048479283 @default.
- W2092014174 cites W2071946013 @default.
- W2092014174 cites W2074051982 @default.
- W2092014174 cites W2077812123 @default.
- W2092014174 cites W2080678920 @default.
- W2092014174 cites W2081060219 @default.
- W2092014174 cites W2081395451 @default.
- W2092014174 cites W2084332766 @default.
- W2092014174 cites W2089593597 @default.
- W2092014174 cites W2092271015 @default.
- W2092014174 cites W2097433021 @default.
- W2092014174 cites W2100904149 @default.
- W2092014174 cites W2110028533 @default.
- W2092014174 cites W2129092046 @default.
- W2092014174 cites W2135271960 @default.
- W2092014174 cites W2152318693 @default.
- W2092014174 cites W2153734830 @default.
- W2092014174 cites W2154881226 @default.
- W2092014174 cites W2156448847 @default.
- W2092014174 cites W2164655645 @default.
- W2092014174 cites W3099854634 @default.
- W2092014174 cites W3204351380 @default.
- W2092014174 cites W95161310 @default.
- W2092014174 doi "https://doi.org/10.1016/s1568-9972(02)00080-0" @default.
- W2092014174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12848977" @default.
- W2092014174 hasPublicationYear "2002" @default.
- W2092014174 type Work @default.
- W2092014174 sameAs 2092014174 @default.
- W2092014174 citedByCount "76" @default.
- W2092014174 countsByYear W20920141742012 @default.
- W2092014174 countsByYear W20920141742013 @default.
- W2092014174 countsByYear W20920141742014 @default.
- W2092014174 countsByYear W20920141742015 @default.
- W2092014174 countsByYear W20920141742016 @default.
- W2092014174 countsByYear W20920141742019 @default.
- W2092014174 countsByYear W20920141742020 @default.
- W2092014174 countsByYear W20920141742022 @default.
- W2092014174 countsByYear W20920141742023 @default.
- W2092014174 crossrefType "journal-article" @default.
- W2092014174 hasAuthorship W2092014174A5033876610 @default.
- W2092014174 hasAuthorship W2092014174A5066868627 @default.
- W2092014174 hasAuthorship W2092014174A5068884058 @default.
- W2092014174 hasConcept C142724271 @default.
- W2092014174 hasConcept C151730666 @default.
- W2092014174 hasConcept C159047783 @default.
- W2092014174 hasConcept C159654299 @default.
- W2092014174 hasConcept C163764329 @default.
- W2092014174 hasConcept C169760540 @default.
- W2092014174 hasConcept C195616568 @default.
- W2092014174 hasConcept C203014093 @default.
- W2092014174 hasConcept C2777119779 @default.
- W2092014174 hasConcept C2778531937 @default.
- W2092014174 hasConcept C2778609137 @default.
- W2092014174 hasConcept C2779134260 @default.
- W2092014174 hasConcept C2779343474 @default.
- W2092014174 hasConcept C2780130043 @default.
- W2092014174 hasConcept C2780640218 @default.
- W2092014174 hasConcept C2780942790 @default.
- W2092014174 hasConcept C529278444 @default.
- W2092014174 hasConcept C71924100 @default.
- W2092014174 hasConcept C86803240 @default.
- W2092014174 hasConceptScore W2092014174C142724271 @default.
- W2092014174 hasConceptScore W2092014174C151730666 @default.
- W2092014174 hasConceptScore W2092014174C159047783 @default.
- W2092014174 hasConceptScore W2092014174C159654299 @default.
- W2092014174 hasConceptScore W2092014174C163764329 @default.
- W2092014174 hasConceptScore W2092014174C169760540 @default.
- W2092014174 hasConceptScore W2092014174C195616568 @default.
- W2092014174 hasConceptScore W2092014174C203014093 @default.
- W2092014174 hasConceptScore W2092014174C2777119779 @default.
- W2092014174 hasConceptScore W2092014174C2778531937 @default.
- W2092014174 hasConceptScore W2092014174C2778609137 @default.
- W2092014174 hasConceptScore W2092014174C2779134260 @default.