FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092016046> ?p ?o ?g. }

• W2092016046 endingPage "4016" @default.
• W2092016046 startingPage "4005" @default.
• W2092016046 abstract "The olfactory bulb (OB) is the first site for the processing of olfactory information in the brain and its deregulation is associated with neurodegenerative disorders. Although different efforts have been made to characterize the human brain proteome in depth, the protein composition of the human OB remains largely unexplored. We have performed a comprehensive analysis of the human OB proteome employing protein and peptide fractionation methods followed by LC-MS/MS, identifying 1529 protein species, corresponding to 1466 unique proteins, which represents a 7-fold increase in proteome coverage with respect to previous OB proteome descriptions from translational models. Bioinformatic analyses revealed that protein components of the OB participated in a plethora of biological process highlighting hydrolase and phosphatase activities and nucleotide and RNA binding activities. Interestingly, 631 OB proteins identified were not previously described in protein datasets derived from large-scale Human Brain Proteome Project (HBPP) studies. In particular, a subset of these differential proteins was mainly involved in axon guidance, opioid signaling, neurotransmitter receptor binding, and synaptic plasticity. Taken together, these results increase our knowledge about the molecular composition of the human OB and may be useful to understand the molecular basis of the olfactory system and the etiology of its disorders." @default.
• W2092016046 created "2016-06-24" @default.
• W2092016046 creator A5006711564 @default.
• W2092016046 creator A5075567314 @default.
• W2092016046 creator A5076205150 @default.
• W2092016046 date "2012-07-01" @default.
• W2092016046 modified "2023-10-14" @default.
• W2092016046 title "Proteomic atlas of the human olfactory bulb" @default.
• W2092016046 cites W1483715699 @default.
• W2092016046 cites W1498735063 @default.
• W2092016046 cites W1719457529 @default.
• W2092016046 cites W1968141749 @default.
• W2092016046 cites W1968236935 @default.
• W2092016046 cites W1968334513 @default.
• W2092016046 cites W1970192770 @default.
• W2092016046 cites W1973085414 @default.
• W2092016046 cites W1974504921 @default.
• W2092016046 cites W1980888440 @default.
• W2092016046 cites W1982136807 @default.
• W2092016046 cites W1988190047 @default.
• W2092016046 cites W1988975207 @default.
• W2092016046 cites W1990704212 @default.
• W2092016046 cites W1993457485 @default.
• W2092016046 cites W1994607750 @default.
• W2092016046 cites W1999922250 @default.
• W2092016046 cites W2002016207 @default.
• W2092016046 cites W2005086972 @default.
• W2092016046 cites W2006803248 @default.
• W2092016046 cites W2011867368 @default.
• W2092016046 cites W2016748026 @default.
• W2092016046 cites W2017119776 @default.
• W2092016046 cites W2025836555 @default.
• W2092016046 cites W2028329539 @default.
• W2092016046 cites W2029091584 @default.
• W2092016046 cites W2032864009 @default.
• W2092016046 cites W2034337662 @default.
• W2092016046 cites W2036737669 @default.
• W2092016046 cites W2039945427 @default.
• W2092016046 cites W2042151879 @default.
• W2092016046 cites W2042622145 @default.
• W2092016046 cites W2045757340 @default.
• W2092016046 cites W2055228471 @default.
• W2092016046 cites W2056550009 @default.
• W2092016046 cites W2060063624 @default.
• W2092016046 cites W2065142466 @default.
• W2092016046 cites W2067914995 @default.
• W2092016046 cites W2071782304 @default.
• W2092016046 cites W2081642846 @default.
• W2092016046 cites W2082254241 @default.
• W2092016046 cites W2084632249 @default.
• W2092016046 cites W2095152070 @default.
• W2092016046 cites W2097186487 @default.
• W2092016046 cites W2098205323 @default.
• W2092016046 cites W2100456324 @default.
• W2092016046 cites W2103017472 @default.
• W2092016046 cites W2107578201 @default.
• W2092016046 cites W2111121844 @default.
• W2092016046 cites W2115129497 @default.
• W2092016046 cites W2119838858 @default.
• W2092016046 cites W2122787130 @default.
• W2092016046 cites W2127172650 @default.
• W2092016046 cites W2131835564 @default.
• W2092016046 cites W2133003904 @default.
• W2092016046 cites W2136134457 @default.
• W2092016046 cites W2139730595 @default.
• W2092016046 cites W2140466067 @default.
• W2092016046 cites W2144092709 @default.
• W2092016046 cites W2152103695 @default.
• W2092016046 cites W2154458690 @default.
• W2092016046 cites W2155644389 @default.
• W2092016046 cites W2160797468 @default.
• W2092016046 cites W2164429277 @default.
• W2092016046 cites W2164975725 @default.
• W2092016046 cites W2165962849 @default.
• W2092016046 cites W2171215275 @default.
• W2092016046 cites W2171862483 @default.
• W2092016046 doi "https://doi.org/10.1016/j.jprot.2012.05.011" @default.
• W2092016046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22609191" @default.
• W2092016046 hasPublicationYear "2012" @default.
• W2092016046 type Work @default.
• W2092016046 sameAs 2092016046 @default.
• W2092016046 citedByCount "29" @default.
• W2092016046 countsByYear W20920160462013 @default.
• W2092016046 countsByYear W20920160462014 @default.
• W2092016046 countsByYear W20920160462015 @default.
• W2092016046 countsByYear W20920160462016 @default.
• W2092016046 countsByYear W20920160462017 @default.
• W2092016046 countsByYear W20920160462018 @default.
• W2092016046 countsByYear W20920160462019 @default.
• W2092016046 countsByYear W20920160462020 @default.
• W2092016046 countsByYear W20920160462021 @default.
• W2092016046 countsByYear W20920160462023 @default.
• W2092016046 crossrefType "journal-article" @default.
• W2092016046 hasAuthorship W2092016046A5006711564 @default.
• W2092016046 hasAuthorship W2092016046A5075567314 @default.
• W2092016046 hasAuthorship W2092016046A5076205150 @default.
• W2092016046 hasConcept C104317684 @default.
• W2092016046 hasConcept C104397665 @default.

• next