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- W2092018061 endingPage "e25961" @default.
- W2092018061 startingPage "e25961" @default.
- W2092018061 abstract "There is much promise in the use of immunotherapy for the treatment of cancer. Approaches such as those using antibodies or adoptive cell transfer can mediate complete tumor regression in a proportion of patients. However, the tumor microenvironment can inhibit immune responses leading to ineffective or suboptimal responses of tumors to immunotherapy in the majority of cases. As our knowledge of the tumor microenvironment increases, many strategies are emerging for changing the immunosuppressive nature of the tumor toward a microenvironment able to support immunity. These strategies aim to enhance the ability of immunotherapies to initiate effective immune responses able to destroy tumors. In this article, we review approaches that use immunomodulators specifically to modify the tumor microenvironment, and their use in combination with other immune-based strategies for cancer therapy." @default.
- W2092018061 created "2016-06-24" @default.
- W2092018061 creator A5026944433 @default.
- W2092018061 creator A5036088140 @default.
- W2092018061 creator A5041956370 @default.
- W2092018061 creator A5055053148 @default.
- W2092018061 creator A5071556658 @default.
- W2092018061 date "2013-08-01" @default.
- W2092018061 modified "2023-10-11" @default.
- W2092018061 title "Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy" @default.
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