FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092045947> ?p ?o ?g. }

• W2092045947 endingPage "490" @default.
• W2092045947 startingPage "487" @default.
• W2092045947 abstract "Nucleic acid electrophoresis separation heavily depends upon gel or nongel sieving matrix. Here we propose a metal ion mediated-capillary electrophoresis (MCE-CE) by utilizing the nonspecific interactions of Mg(2+) and Ca(2+) and demonstrate the size, conformation, or sequence based separation and characterization of versatile nucleic acid molecules in free solution. Mg(2+) and Ca(2+) can induce DNA separation at the concentrations as low as 100 and 50 muM, respectively. Noteworthy, the two naturally occurring polymorphisms of one base substitution that may change the secondary folding structure or base stacking can be discriminated by MCM-CE, showing its unique capability of resolving length-identical but conformation-different ssDNA. Benefiting from the achieved separation, we further demonstrate that the folding conformation of oligomers and its change caused by single base substitution can be promptly sensed by online coupled fluorescence polarization. We anticipate that this method will be applicable in length polymorphism analysis, single-strand polymorphism analysis, hybridization analysis, microRNA analysis, and study of protein-nucleic acid interactions and the conformation-function relationship." @default.
• W2092045947 created "2016-06-24" @default.
• W2092045947 creator A5003774349 @default.
• W2092045947 creator A5004565086 @default.
• W2092045947 creator A5008405013 @default.
• W2092045947 creator A5037096872 @default.
• W2092045947 creator A5042499241 @default.
• W2092045947 creator A5059721592 @default.
• W2092045947 creator A5086326013 @default.
• W2092045947 date "2009-12-23" @default.
• W2092045947 modified "2023-09-26" @default.
• W2092045947 title "Metal Cation Mediated-Capillary Electrophoresis of Nucleic Acids" @default.
• W2092045947 cites W144423133 @default.
• W2092045947 cites W1964860759 @default.
• W2092045947 cites W1976830444 @default.
• W2092045947 cites W1976864947 @default.
• W2092045947 cites W1994708868 @default.
• W2092045947 cites W2007406795 @default.
• W2092045947 cites W2014914281 @default.
• W2092045947 cites W2015729536 @default.
• W2092045947 cites W2015858554 @default.
• W2092045947 cites W2017906697 @default.
• W2092045947 cites W2033713657 @default.
• W2092045947 cites W2042334273 @default.
• W2092045947 cites W2045347584 @default.
• W2092045947 cites W2045415172 @default.
• W2092045947 cites W2056080046 @default.
• W2092045947 cites W2057026876 @default.
• W2092045947 cites W2059191790 @default.
• W2092045947 cites W2078379428 @default.
• W2092045947 cites W2079321730 @default.
• W2092045947 cites W2080075741 @default.
• W2092045947 cites W2089001345 @default.
• W2092045947 cites W2089774788 @default.
• W2092045947 cites W2097687472 @default.
• W2092045947 cites W2116477480 @default.
• W2092045947 cites W2165764599 @default.
• W2092045947 doi "https://doi.org/10.1021/ac9025708" @default.
• W2092045947 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20030314" @default.
• W2092045947 hasPublicationYear "2009" @default.
• W2092045947 type Work @default.
• W2092045947 sameAs 2092045947 @default.
• W2092045947 citedByCount "16" @default.
• W2092045947 countsByYear W20920459472012 @default.
• W2092045947 countsByYear W20920459472015 @default.
• W2092045947 countsByYear W20920459472016 @default.
• W2092045947 countsByYear W20920459472019 @default.
• W2092045947 countsByYear W20920459472020 @default.
• W2092045947 countsByYear W20920459472022 @default.
• W2092045947 crossrefType "journal-article" @default.
• W2092045947 hasAuthorship W2092045947A5003774349 @default.
• W2092045947 hasAuthorship W2092045947A5004565086 @default.
• W2092045947 hasAuthorship W2092045947A5008405013 @default.
• W2092045947 hasAuthorship W2092045947A5037096872 @default.
• W2092045947 hasAuthorship W2092045947A5042499241 @default.
• W2092045947 hasAuthorship W2092045947A5059721592 @default.
• W2092045947 hasAuthorship W2092045947A5086326013 @default.
• W2092045947 hasBestOaLocation W20920459471 @default.
• W2092045947 hasConcept C104317684 @default.
• W2092045947 hasConcept C111357860 @default.
• W2092045947 hasConcept C119599485 @default.
• W2092045947 hasConcept C12554922 @default.
• W2092045947 hasConcept C126142528 @default.
• W2092045947 hasConcept C126307556 @default.
• W2092045947 hasConcept C127413603 @default.
• W2092045947 hasConcept C178790620 @default.
• W2092045947 hasConcept C185581394 @default.
• W2092045947 hasConcept C185592680 @default.
• W2092045947 hasConcept C24107716 @default.
• W2092045947 hasConcept C2776545253 @default.
• W2092045947 hasConcept C2900643 @default.
• W2092045947 hasConcept C33347731 @default.
• W2092045947 hasConcept C40250595 @default.
• W2092045947 hasConcept C41625074 @default.
• W2092045947 hasConcept C43617362 @default.
• W2092045947 hasConcept C552990157 @default.
• W2092045947 hasConcept C55493867 @default.
• W2092045947 hasConcept C67705224 @default.
• W2092045947 hasConcept C8010536 @default.
• W2092045947 hasConcept C86803240 @default.
• W2092045947 hasConceptScore W2092045947C104317684 @default.
• W2092045947 hasConceptScore W2092045947C111357860 @default.
• W2092045947 hasConceptScore W2092045947C119599485 @default.
• W2092045947 hasConceptScore W2092045947C12554922 @default.
• W2092045947 hasConceptScore W2092045947C126142528 @default.
• W2092045947 hasConceptScore W2092045947C126307556 @default.
• W2092045947 hasConceptScore W2092045947C127413603 @default.
• W2092045947 hasConceptScore W2092045947C178790620 @default.
• W2092045947 hasConceptScore W2092045947C185581394 @default.
• W2092045947 hasConceptScore W2092045947C185592680 @default.
• W2092045947 hasConceptScore W2092045947C24107716 @default.
• W2092045947 hasConceptScore W2092045947C2776545253 @default.
• W2092045947 hasConceptScore W2092045947C2900643 @default.
• W2092045947 hasConceptScore W2092045947C33347731 @default.
• W2092045947 hasConceptScore W2092045947C40250595 @default.
• W2092045947 hasConceptScore W2092045947C41625074 @default.
• W2092045947 hasConceptScore W2092045947C43617362 @default.
• W2092045947 hasConceptScore W2092045947C552990157 @default.

• next