FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092051242> ?p ?o ?g. }

• W2092051242 endingPage "137" @default.
• W2092051242 startingPage "131" @default.
• W2092051242 abstract "Objective: There is growing interest in investigating the adenosine–dopamine interaction in the ventral striatum. Adenosine plays a role opposite to dopamine in the striatum and adenosine antagonists, like caffeine, produce similar effects to increased dopaminergic neurotransmission in the striatum. In particular, a strong antagonistic interaction between adenosine A2A and dopamine D2 receptors takes place in the striopallidal GABAergic neurones. Therefore, adenosine agonists or uptake inhibitors provide a potential new treatment for schizophrenia. We undertook a pilot trial to investigate whether the combination of haloperidol with dipyridamole, an uptake inhibitor of adenosine, was more effective than haloperidol alone. Methods: Thirty patients who met the DSM IV criteria for schizophrenia completed the study. Patients were allocated in a random fashion, 16 to haloperidol 20 mg/day plus dipyridamole 75 mg/day and 14 to haloperidol 20 mg/day plus placebo. Results: Although both protocols significantly decreased the score of the positive, negative and general psychopathological symptoms over the trial period, the combination of haloperidol and dipyridamole was significantly better than haloperidol alone in decreasing positive and general psychopathology symptoms as well as PANSS total scores. Conclusion: Dipyridamole may be of therapeutic benefit in treating schizophrenia in combination with neuroleptics. However, a larger study to confirm our results is warranted." @default.
• W2092051242 created "2016-06-24" @default.
• W2092051242 creator A5003549957 @default.
• W2092051242 creator A5028702311 @default.
• W2092051242 creator A5074054395 @default.
• W2092051242 creator A5080730095 @default.
• W2092051242 creator A5088810181 @default.
• W2092051242 date "2000-04-01" @default.
• W2092051242 modified "2023-10-04" @default.
• W2092051242 title "Dipyridamole in the treatment of schizophrenia: adenosine-dopamine receptor interactions" @default.
• W2092051242 cites W1502439265 @default.
• W2092051242 cites W1735144118 @default.
• W2092051242 cites W180111337 @default.
• W2092051242 cites W1965552866 @default.
• W2092051242 cites W1975750741 @default.
• W2092051242 cites W1976408965 @default.
• W2092051242 cites W1981480470 @default.
• W2092051242 cites W1982058167 @default.
• W2092051242 cites W1984871702 @default.
• W2092051242 cites W1985575783 @default.
• W2092051242 cites W1997586459 @default.
• W2092051242 cites W1999116988 @default.
• W2092051242 cites W2004377158 @default.
• W2092051242 cites W2017983575 @default.
• W2092051242 cites W2022883582 @default.
• W2092051242 cites W2024469932 @default.
• W2092051242 cites W2034290472 @default.
• W2092051242 cites W2035971243 @default.
• W2092051242 cites W2045047823 @default.
• W2092051242 cites W2048423134 @default.
• W2092051242 cites W2050121560 @default.
• W2092051242 cites W2053271940 @default.
• W2092051242 cites W2053650795 @default.
• W2092051242 cites W2054484015 @default.
• W2092051242 cites W2054683291 @default.
• W2092051242 cites W2058473786 @default.
• W2092051242 cites W2062813669 @default.
• W2092051242 cites W2072486526 @default.
• W2092051242 cites W2075900490 @default.
• W2092051242 cites W2079265669 @default.
• W2092051242 cites W2080561657 @default.
• W2092051242 cites W2119619841 @default.
• W2092051242 cites W2121713405 @default.
• W2092051242 cites W2127622391 @default.
• W2092051242 cites W2140606211 @default.
• W2092051242 cites W2493179129 @default.
• W2092051242 cites W4230625092 @default.
• W2092051242 cites W592854807 @default.
• W2092051242 doi "https://doi.org/10.1046/j.1365-2710.2000.00273.x" @default.
• W2092051242 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10849191" @default.
• W2092051242 hasPublicationYear "2000" @default.
• W2092051242 type Work @default.
• W2092051242 sameAs 2092051242 @default.
• W2092051242 citedByCount "95" @default.
• W2092051242 countsByYear W20920512422012 @default.
• W2092051242 countsByYear W20920512422013 @default.
• W2092051242 countsByYear W20920512422014 @default.
• W2092051242 countsByYear W20920512422015 @default.
• W2092051242 countsByYear W20920512422016 @default.
• W2092051242 countsByYear W20920512422017 @default.
• W2092051242 countsByYear W20920512422018 @default.
• W2092051242 countsByYear W20920512422019 @default.
• W2092051242 countsByYear W20920512422020 @default.
• W2092051242 countsByYear W20920512422021 @default.
• W2092051242 countsByYear W20920512422022 @default.
• W2092051242 countsByYear W20920512422023 @default.
• W2092051242 crossrefType "journal-article" @default.
• W2092051242 hasAuthorship W2092051242A5003549957 @default.
• W2092051242 hasAuthorship W2092051242A5028702311 @default.
• W2092051242 hasAuthorship W2092051242A5074054395 @default.
• W2092051242 hasAuthorship W2092051242A5080730095 @default.
• W2092051242 hasAuthorship W2092051242A5088810181 @default.
• W2092051242 hasBestOaLocation W20920512421 @default.
• W2092051242 hasConcept C118552586 @default.
• W2092051242 hasConcept C126322002 @default.
• W2092051242 hasConcept C137183658 @default.
• W2092051242 hasConcept C15744967 @default.
• W2092051242 hasConcept C2776412080 @default.
• W2092051242 hasConcept C2776890861 @default.
• W2092051242 hasConcept C2776991684 @default.
• W2092051242 hasConcept C2780062018 @default.
• W2092051242 hasConcept C2780948584 @default.
• W2092051242 hasConcept C44208683 @default.
• W2092051242 hasConcept C513476851 @default.
• W2092051242 hasConcept C71924100 @default.
• W2092051242 hasConcept C98274493 @default.
• W2092051242 hasConceptScore W2092051242C118552586 @default.
• W2092051242 hasConceptScore W2092051242C126322002 @default.
• W2092051242 hasConceptScore W2092051242C137183658 @default.
• W2092051242 hasConceptScore W2092051242C15744967 @default.
• W2092051242 hasConceptScore W2092051242C2776412080 @default.
• W2092051242 hasConceptScore W2092051242C2776890861 @default.
• W2092051242 hasConceptScore W2092051242C2776991684 @default.
• W2092051242 hasConceptScore W2092051242C2780062018 @default.
• W2092051242 hasConceptScore W2092051242C2780948584 @default.
• W2092051242 hasConceptScore W2092051242C44208683 @default.
• W2092051242 hasConceptScore W2092051242C513476851 @default.
• W2092051242 hasConceptScore W2092051242C71924100 @default.

• next