Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092080503> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2092080503 abstract "The effects of dopexamine and dopamine on mesenteric ischemia during reperfusion following aortic cross-clamping are not known. We determined intramucosal tonometric PCO2 and PCO2 gap using a rat model of supraceliac aortic cross-clamping and declamping.Under pentobarbital and fentanyl anesthesia, 24 rats were surgically instrumented with arterial, right atrial, and portal venous catheters, ultrasonic flowprobes for measurements of abdominal aortic, superior mesenteric and carotid artery blood flow, and a pediatric tonometer for intestinal mucosal PCO2 measurements. Rats were randomized to receive a continuous infusion of dopexamine (10 x microg(-1) x kg(-1) x min(-1), n=8), dopamine (10 microg x kg(-1) x min(-1), n=8 ), or physiologic saline (control, n= 8), infused at a rate of 4 ml x kg(-1) x h(-1), administered throughout the experimental protocol. After 30 min of drug infusion, the aorta was cross-clamped at the supraceliac level for 30 min. Reperfusion following declamping was observed for 180 min.Intestinal tonometric PCO2 remained unchanged during drug treatment before aortic cross-clamping, increased similarly in all groups following declamping during early reperfusion, and recovered to baseline within 30 min of reperfusion. Dopexamine treatment was associated with higher lactate levels and increased heart rate (P<0.05) during aortic cross-clamping.1) Mesenteric ischemia, determined by intestinal tonometric PCO2 and PCO2 gap, recovers within 30 min of reperfusion following 30 min of aortic cross-clamping irrespective of drug treatment and, 2) dopexamine induced higher lactate levels and increased heart rate during aortic cross-clamping and should be carefully analyzed for potentially adverse effects on cardiac function." @default.
- W2092080503 created "2016-06-24" @default.
- W2092080503 creator A5056255906 @default.
- W2092080503 creator A5091158151 @default.
- W2092080503 date "2000-03-01" @default.
- W2092080503 modified "2023-10-16" @default.
- W2092080503 title "Supraceliac aortic cross-clamping and declamping. Effects of dopexamine and dopamine on systemic and mesenteric hemodynamics, metabolism and intestinal tonometry in a rat model" @default.
- W2092080503 cites W1791447317 @default.
- W2092080503 cites W184853823 @default.
- W2092080503 cites W1967929888 @default.
- W2092080503 cites W1980983684 @default.
- W2092080503 cites W2002008524 @default.
- W2092080503 cites W2007897281 @default.
- W2092080503 cites W2017812199 @default.
- W2092080503 cites W2021812349 @default.
- W2092080503 cites W2025740210 @default.
- W2092080503 cites W2033744605 @default.
- W2092080503 cites W2049025916 @default.
- W2092080503 cites W2054058189 @default.
- W2092080503 cites W2076596465 @default.
- W2092080503 cites W2079555223 @default.
- W2092080503 cites W2080897465 @default.
- W2092080503 cites W2090136511 @default.
- W2092080503 cites W2125563414 @default.
- W2092080503 cites W2141596327 @default.
- W2092080503 cites W2147735025 @default.
- W2092080503 cites W2151384655 @default.
- W2092080503 cites W2313221069 @default.
- W2092080503 cites W2463157785 @default.
- W2092080503 cites W4297754387 @default.
- W2092080503 doi "https://doi.org/10.1034/j.1399-6576.2000.440305.x" @default.
- W2092080503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10714835" @default.
- W2092080503 hasPublicationYear "2000" @default.
- W2092080503 type Work @default.
- W2092080503 sameAs 2092080503 @default.
- W2092080503 citedByCount "15" @default.
- W2092080503 countsByYear W20920805032012 @default.
- W2092080503 countsByYear W20920805032016 @default.
- W2092080503 countsByYear W20920805032023 @default.
- W2092080503 crossrefType "journal-article" @default.
- W2092080503 hasAuthorship W2092080503A5056255906 @default.
- W2092080503 hasAuthorship W2092080503A5091158151 @default.
- W2092080503 hasConcept C126322002 @default.
- W2092080503 hasConcept C139940330 @default.
- W2092080503 hasConcept C164705383 @default.
- W2092080503 hasConcept C178853913 @default.
- W2092080503 hasConcept C2777140959 @default.
- W2092080503 hasConcept C2779980429 @default.
- W2092080503 hasConcept C2780520971 @default.
- W2092080503 hasConcept C2781046184 @default.
- W2092080503 hasConcept C42219234 @default.
- W2092080503 hasConcept C71924100 @default.
- W2092080503 hasConceptScore W2092080503C126322002 @default.
- W2092080503 hasConceptScore W2092080503C139940330 @default.
- W2092080503 hasConceptScore W2092080503C164705383 @default.
- W2092080503 hasConceptScore W2092080503C178853913 @default.
- W2092080503 hasConceptScore W2092080503C2777140959 @default.
- W2092080503 hasConceptScore W2092080503C2779980429 @default.
- W2092080503 hasConceptScore W2092080503C2780520971 @default.
- W2092080503 hasConceptScore W2092080503C2781046184 @default.
- W2092080503 hasConceptScore W2092080503C42219234 @default.
- W2092080503 hasConceptScore W2092080503C71924100 @default.
- W2092080503 hasLocation W20920805031 @default.
- W2092080503 hasLocation W20920805032 @default.
- W2092080503 hasOpenAccess W2092080503 @default.
- W2092080503 hasPrimaryLocation W20920805031 @default.
- W2092080503 hasRelatedWork W1965666150 @default.
- W2092080503 hasRelatedWork W2079245118 @default.
- W2092080503 hasRelatedWork W2092080503 @default.
- W2092080503 hasRelatedWork W2108774925 @default.
- W2092080503 hasRelatedWork W2123130971 @default.
- W2092080503 hasRelatedWork W2319347875 @default.
- W2092080503 hasRelatedWork W2376589155 @default.
- W2092080503 hasRelatedWork W2404097744 @default.
- W2092080503 hasRelatedWork W2414254489 @default.
- W2092080503 hasRelatedWork W2015673411 @default.
- W2092080503 isParatext "false" @default.
- W2092080503 isRetracted "false" @default.
- W2092080503 magId "2092080503" @default.
- W2092080503 workType "article" @default.