FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092096076> ?p ?o ?g. }

• W2092096076 endingPage "542" @default.
• W2092096076 startingPage "538" @default.
• W2092096076 abstract "ABSTRACT Introduction 2‐Chlorodeoxyadenosine (cladribine or 2‐CdA) is a purine analogue that has been used successfully in hairy cell leukaemia (HCL). Moreover, it has been increasingly used to treat chronic lymphoproliferative syndromes and paediatric acute myeloid leukaemia. Cutaneous side‐effects associated with this drug have seldom been described in cases of HCL. Patients and methods We describe three patients with chronic lymphocytic leukaemia that presented generalized skin eruptions after treatment with 2‐CdA. Results All patients had advanced disease, receiving 2‐CdA as a second or third line chemotherapy. Skin lesions were severe and chemotherapy had to be discontinued. Histological examination of skin biopsies showed an eosinophil‐rich infiltrate with flame figures, similar to what is observed in Wells’ syndrome (eosinophilic cellulitis). Corticosteroids were effective to control the eruptions. Conclusions Cutaneous adverse reactions associated with 2‐CdA have seldom been observed in the treatment of HCL. However, as this purine analogue has been used in more advanced cases these may be more frequent and severe. The pathophysiology of these lesions is unclear, but it is probably related to drug‐induced change in T‐cell imbalance in severely immunosuppressed patients." @default.
• W2092096076 created "2016-06-24" @default.
• W2092096076 creator A5003584861 @default.
• W2092096076 creator A5045839732 @default.
• W2092096076 creator A5048799203 @default.
• W2092096076 creator A5050856686 @default.
• W2092096076 creator A5067255225 @default.
• W2092096076 creator A5084306768 @default.
• W2092096076 date "2004-07-02" @default.
• W2092096076 modified "2023-10-12" @default.
• W2092096076 title "Cutaneous adverse reaction to 2-chlorodeoxyadenosine with histological flame figures in patients with chronic lymphocytic leukaemia" @default.
• W2092096076 cites W129142841 @default.
• W2092096076 cites W1967010089 @default.
• W2092096076 cites W1978447854 @default.
• W2092096076 cites W1986476887 @default.
• W2092096076 cites W1990850207 @default.
• W2092096076 cites W2000179414 @default.
• W2092096076 cites W2031145495 @default.
• W2092096076 cites W2031388944 @default.
• W2092096076 cites W2058689004 @default.
• W2092096076 cites W2067493324 @default.
• W2092096076 cites W2073282549 @default.
• W2092096076 cites W2073544046 @default.
• W2092096076 cites W2089990542 @default.
• W2092096076 cites W2092346592 @default.
• W2092096076 cites W2094330363 @default.
• W2092096076 cites W2096991928 @default.
• W2092096076 cites W2113018766 @default.
• W2092096076 cites W2114606683 @default.
• W2092096076 cites W2126434145 @default.
• W2092096076 cites W2136726402 @default.
• W2092096076 cites W2329731459 @default.
• W2092096076 cites W2333828318 @default.
• W2092096076 cites W2409713754 @default.
• W2092096076 cites W2473829050 @default.
• W2092096076 cites W4233161682 @default.
• W2092096076 cites W4237961993 @default.
• W2092096076 cites W4241708812 @default.
• W2092096076 cites W4242383674 @default.
• W2092096076 doi "https://doi.org/10.1111/j.1468-3083.2004.00969.x" @default.
• W2092096076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15324388" @default.
• W2092096076 hasPublicationYear "2004" @default.
• W2092096076 type Work @default.
• W2092096076 sameAs 2092096076 @default.
• W2092096076 citedByCount "26" @default.
• W2092096076 countsByYear W20920960762013 @default.
• W2092096076 countsByYear W20920960762014 @default.
• W2092096076 countsByYear W20920960762015 @default.
• W2092096076 countsByYear W20920960762016 @default.
• W2092096076 countsByYear W20920960762017 @default.
• W2092096076 countsByYear W20920960762019 @default.
• W2092096076 countsByYear W20920960762020 @default.
• W2092096076 countsByYear W20920960762022 @default.
• W2092096076 crossrefType "journal-article" @default.
• W2092096076 hasAuthorship W2092096076A5003584861 @default.
• W2092096076 hasAuthorship W2092096076A5045839732 @default.
• W2092096076 hasAuthorship W2092096076A5048799203 @default.
• W2092096076 hasAuthorship W2092096076A5050856686 @default.
• W2092096076 hasAuthorship W2092096076A5067255225 @default.
• W2092096076 hasAuthorship W2092096076A5084306768 @default.
• W2092096076 hasConcept C109246011 @default.
• W2092096076 hasConcept C126322002 @default.
• W2092096076 hasConcept C16005928 @default.
• W2092096076 hasConcept C181199279 @default.
• W2092096076 hasConcept C185592680 @default.
• W2092096076 hasConcept C197934379 @default.
• W2092096076 hasConcept C2776476023 @default.
• W2092096076 hasConcept C2776694085 @default.
• W2092096076 hasConcept C2779200787 @default.
• W2092096076 hasConcept C55493867 @default.
• W2092096076 hasConcept C71924100 @default.
• W2092096076 hasConcept C90924648 @default.
• W2092096076 hasConceptScore W2092096076C109246011 @default.
• W2092096076 hasConceptScore W2092096076C126322002 @default.
• W2092096076 hasConceptScore W2092096076C16005928 @default.
• W2092096076 hasConceptScore W2092096076C181199279 @default.
• W2092096076 hasConceptScore W2092096076C185592680 @default.
• W2092096076 hasConceptScore W2092096076C197934379 @default.
• W2092096076 hasConceptScore W2092096076C2776476023 @default.
• W2092096076 hasConceptScore W2092096076C2776694085 @default.
• W2092096076 hasConceptScore W2092096076C2779200787 @default.
• W2092096076 hasConceptScore W2092096076C55493867 @default.
• W2092096076 hasConceptScore W2092096076C71924100 @default.
• W2092096076 hasConceptScore W2092096076C90924648 @default.
• W2092096076 hasIssue "5" @default.
• W2092096076 hasLocation W20920960761 @default.
• W2092096076 hasLocation W20920960762 @default.
• W2092096076 hasOpenAccess W2092096076 @default.
• W2092096076 hasPrimaryLocation W20920960761 @default.
• W2092096076 hasRelatedWork W1998497846 @default.
• W2092096076 hasRelatedWork W2040184883 @default.
• W2092096076 hasRelatedWork W2047980919 @default.
• W2092096076 hasRelatedWork W2115139696 @default.
• W2092096076 hasRelatedWork W2128515102 @default.
• W2092096076 hasRelatedWork W2173057084 @default.
• W2092096076 hasRelatedWork W2327728819 @default.
• W2092096076 hasRelatedWork W2888926240 @default.
• W2092096076 hasRelatedWork W3032044162 @default.

• next