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• W2092114527 startingPage "RA44" @default.
• W2092114527 abstract "Nitric oxide (NO), a vasoactive gas that can freely diffuse into the cell, has many physiological effects in various cell types. Since 1986, numerous studies of ischemic preconditioning against ischemia-reperfusion (I/R) injury have been undertaken and the roles of the NO signaling pathway in cardioprotection have been explored. Many studies have confirmed the effect of NO and that its relative signaling pathway is important for preconditioning of the cardioprotective effect. The NO signaling against I/R injury targeted on the mitochondria is believed to be the end-target for cardioprotection. If the NO signaling pathway is disrupted or inhibited, cardioprotection by preconditioning disappears. During preconditioning, signaling is initiated from the sarcolemmal membrane, and then spread into the cytoplasm via many series of enzymes, including nitric oxide synthase (NOS), the NO-producing enzyme, soluble guanylyl cyclase (sGC), and protein kinase G (PKG). Finally, the signal is transmitted into the mitochondria, where the cardioprotective effect occurs. It is now well established that mitochondria act to protect the heart against I/R injury via the opening of the mitochondrial ATP-sensitive K+ channel and the inhibition of mitochondrial permeability transition (MPT). This knowledge may be useful in developing novel strategies for clinical cardioprotection from I/R injury." @default.
• W2092114527 created "2016-06-24" @default.
• W2092114527 creator A5025939163 @default.
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• W2092114527 date "2011-01-01" @default.
• W2092114527 modified "2023-09-27" @default.
• W2092114527 title "Roles of the nitric oxide signaling pathway in cardiac ischemic preconditioning against myocardial ischemia-reperfusion injury" @default.
• W2092114527 cites W1605869634 @default.
• W2092114527 cites W1965693429 @default.
• W2092114527 cites W1966773468 @default.
• W2092114527 cites W1974707946 @default.
• W2092114527 cites W1976518076 @default.
• W2092114527 cites W1977407669 @default.
• W2092114527 cites W1979119013 @default.
• W2092114527 cites W1986161535 @default.
• W2092114527 cites W1986905765 @default.
• W2092114527 cites W1987664769 @default.
• W2092114527 cites W1990527302 @default.
• W2092114527 cites W1991365337 @default.
• W2092114527 cites W1991379056 @default.
• W2092114527 cites W1992255196 @default.
• W2092114527 cites W1996867825 @default.
• W2092114527 cites W2002597119 @default.
• W2092114527 cites W2003937760 @default.
• W2092114527 cites W2004999698 @default.
• W2092114527 cites W2010516222 @default.
• W2092114527 cites W2012763790 @default.
• W2092114527 cites W2014315683 @default.
• W2092114527 cites W2018638869 @default.
• W2092114527 cites W2020796941 @default.
• W2092114527 cites W2021917695 @default.
• W2092114527 cites W2022255691 @default.
• W2092114527 cites W2029077404 @default.
• W2092114527 cites W2031733455 @default.
• W2092114527 cites W2032203291 @default.
• W2092114527 cites W2033780408 @default.
• W2092114527 cites W2038367443 @default.
• W2092114527 cites W2040603631 @default.
• W2092114527 cites W2044609399 @default.
• W2092114527 cites W2046421938 @default.
• W2092114527 cites W2048543877 @default.
• W2092114527 cites W2053586661 @default.
• W2092114527 cites W2053843168 @default.
• W2092114527 cites W2054903524 @default.
• W2092114527 cites W2055642563 @default.
• W2092114527 cites W2061406590 @default.
• W2092114527 cites W2064465533 @default.
• W2092114527 cites W2069959762 @default.
• W2092114527 cites W2080889392 @default.
• W2092114527 cites W2082850842 @default.
• W2092114527 cites W2088759305 @default.
• W2092114527 cites W2088940818 @default.
• W2092114527 cites W2089835963 @default.
• W2092114527 cites W2091300408 @default.
• W2092114527 cites W2093494462 @default.
• W2092114527 cites W2099026280 @default.
• W2092114527 cites W2100143490 @default.
• W2092114527 cites W2103444279 @default.
• W2092114527 cites W2108512127 @default.
• W2092114527 cites W2114647023 @default.
• W2092114527 cites W2116721331 @default.
• W2092114527 cites W2116990057 @default.
• W2092114527 cites W2125369648 @default.
• W2092114527 cites W2126788226 @default.
• W2092114527 cites W2127312355 @default.
• W2092114527 cites W2128745548 @default.
• W2092114527 cites W2130229822 @default.
• W2092114527 cites W2131390930 @default.
• W2092114527 cites W2138932273 @default.
• W2092114527 cites W2145372543 @default.
• W2092114527 cites W2146070419 @default.
• W2092114527 cites W2146217294 @default.
• W2092114527 cites W2150757211 @default.
• W2092114527 cites W2151589110 @default.
• W2092114527 cites W2155967383 @default.
• W2092114527 cites W2156861743 @default.
• W2092114527 cites W2163768568 @default.
• W2092114527 cites W2164334501 @default.
• W2092114527 cites W2166173560 @default.
• W2092114527 cites W2167808720 @default.
• W2092114527 cites W2167953429 @default.
• W2092114527 cites W2169806115 @default.
• W2092114527 cites W4240150566 @default.
• W2092114527 cites W4251114333 @default.
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• W2092114527 doi "https://doi.org/10.12659/msm.881385" @default.
• W2092114527 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3524696" @default.
• W2092114527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21278703" @default.
• W2092114527 hasPublicationYear "2011" @default.
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