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- W2092128565 abstract "In this month's Pediatrics 1 and in an article published previously in the British Medical Journal ,2Uhari and associates of Finland have suggested that xylitol sugar is effective in preventing acute otitis media. The studies tackle the difficult issue of determining the effect of a targeted prevention on the incidence of a disease as complex and multifactorial in its etiology as acute otitis media. The key finding is that xylitol, given as a gum to older children and as a syrup to younger children, decreased the incidence of acute otitis media and the use of antibiotics by approximately one third in both studies. The criteria for the randomization, blinding of observers, and diagnosis of otitis media can be quibbled with but are unlikely to invalidate this impressive and consistent finding in both studies. This is very good news at a time when antibiotic use and consequent antibiotic resistance are increasing rapidly.3 At this point, one should ask, “What is xylitol, what was the rationale for trying xylitol in Finland, and why might it work?” Xylitol is a 5 carbon sugar alcohol …" @default.
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- W2092128565 date "1998-10-01" @default.
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- W2092128565 title "Xylitol Sugar and Acute Otitis Media" @default.
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- W2092128565 doi "https://doi.org/10.1542/peds.102.4.971" @default.
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