FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092133552> ?p ?o ?g. }

• W2092133552 endingPage "1001" @default.
• W2092133552 startingPage "993" @default.
• W2092133552 abstract "HERBERG L. J., I. C. ROSE, F. DAVISON, M. THOM, A. BECKETT AND F. SCARAVILLI. Spontaneous epileptiform seizures but increased resistance to kindled seizures in a mutant Sprague–Dawley rat (mf/mf). PHARMACOL BIOCHEM BEHAV 58(4) 993–1001, 1997.—Approximately 30% of a breeding colony of Sprague–Dawley rats homozygous for an autosomal recessive mutation mf (“mutilated foot”) associated with a peripheral sensory neuropathy have been found unexpectedly to suffer spontaneous epileptiform attacks. Seizures ranged from brief episodes of compulsive running to tonic–clonic convulsions lasting for up to 30 s, recurring at intervals of hours or days. EEG recordings during seizures showed high-voltage 8–10 Hz spike trains that abated over the ensuing 1–2 min. Interictal records were usually normal. Twice-daily kindling of the amygdala (200 μA sinewave for 1.0 s) was unexpectedly ineffective. Most of the rats that had suffered spontaneous seizures failed to develop kindled afterdischarges, even after 30 kindling stimulations. Other mf rats developed prolonged high-amplitude kindled afterdischarges that were arrested at stage 2 and failed to evolve into convulsive seizures. Hippocampal dentate granule cells of kindled mf rats, stained for zinc by Timm’s method, showed significantly less mossy fibre sprouting than wild-type Sprague–Dawley rats after the same number of kindled afterdischarges. A minority of the mf rats tested (2 of 14) kindled normally. Auditory stimulation (n = 23) or stroboscopic flicker (n = 14) failed to elicit seizures or running fits in any mf rat. Peripheral neuropathy corresponding to that in the mf rat, with resistance to kindling and diminished mossy fibre sprouting, have also been reported in transgenic mice with defective p75NGFR neurotrophin receptors. A homologous genetic defect in the rat could account for most of the features of the mf phenotype." @default.
• W2092133552 created "2016-06-24" @default.
• W2092133552 creator A5007463627 @default.
• W2092133552 creator A5020196911 @default.
• W2092133552 creator A5033588723 @default.
• W2092133552 creator A5037457003 @default.
• W2092133552 creator A5044926937 @default.
• W2092133552 creator A5049258088 @default.
• W2092133552 date "1997-12-01" @default.
• W2092133552 modified "2023-09-25" @default.
• W2092133552 title "Spontaneous Epileptiform Seizures but Increased Resistance to Kindled Seizures in a Mutant Sprague–Dawley Rat (mf/mf)" @default.
• W2092133552 cites W1231883350 @default.
• W2092133552 cites W1574757902 @default.
• W2092133552 cites W180711315 @default.
• W2092133552 cites W1817626063 @default.
• W2092133552 cites W1946506165 @default.
• W2092133552 cites W1964731698 @default.
• W2092133552 cites W1970014384 @default.
• W2092133552 cites W1974972283 @default.
• W2092133552 cites W1975911537 @default.
• W2092133552 cites W1979357747 @default.
• W2092133552 cites W1980133293 @default.
• W2092133552 cites W1981881657 @default.
• W2092133552 cites W1982043728 @default.
• W2092133552 cites W1982909076 @default.
• W2092133552 cites W1987313743 @default.
• W2092133552 cites W1987904402 @default.
• W2092133552 cites W1994312297 @default.
• W2092133552 cites W1997309303 @default.
• W2092133552 cites W1998330442 @default.
• W2092133552 cites W1999100440 @default.
• W2092133552 cites W2000304313 @default.
• W2092133552 cites W2003465634 @default.
• W2092133552 cites W2006968505 @default.
• W2092133552 cites W2008305925 @default.
• W2092133552 cites W2014447344 @default.
• W2092133552 cites W2015755811 @default.
• W2092133552 cites W2018112449 @default.
• W2092133552 cites W2018707500 @default.
• W2092133552 cites W2023595690 @default.
• W2092133552 cites W2026315023 @default.
• W2092133552 cites W2030239560 @default.
• W2092133552 cites W2033195474 @default.
• W2092133552 cites W2035562497 @default.
• W2092133552 cites W2038576003 @default.
• W2092133552 cites W2038697251 @default.
• W2092133552 cites W2039812926 @default.
• W2092133552 cites W2041525670 @default.
• W2092133552 cites W2041787072 @default.
• W2092133552 cites W2042796093 @default.
• W2092133552 cites W2043630477 @default.
• W2092133552 cites W2045515851 @default.
• W2092133552 cites W2045595863 @default.
• W2092133552 cites W2046748951 @default.
• W2092133552 cites W2061050597 @default.
• W2092133552 cites W2069831153 @default.
• W2092133552 cites W2076843536 @default.
• W2092133552 cites W2076894554 @default.
• W2092133552 cites W2077369265 @default.
• W2092133552 cites W2078316783 @default.
• W2092133552 cites W2078333644 @default.
• W2092133552 cites W2081975691 @default.
• W2092133552 cites W2084212152 @default.
• W2092133552 cites W2087201913 @default.
• W2092133552 cites W2088868056 @default.
• W2092133552 cites W2093320992 @default.
• W2092133552 cites W2103946141 @default.
• W2092133552 cites W2116722625 @default.
• W2092133552 cites W2116864608 @default.
• W2092133552 cites W2124658655 @default.
• W2092133552 cites W2138730880 @default.
• W2092133552 cites W2142746886 @default.
• W2092133552 cites W2155170837 @default.
• W2092133552 cites W2163815564 @default.
• W2092133552 cites W2198196898 @default.
• W2092133552 cites W2483333754 @default.
• W2092133552 cites W3105898142 @default.
• W2092133552 cites W34779387 @default.
• W2092133552 cites W2606417122 @default.
• W2092133552 doi "https://doi.org/10.1016/s0091-3057(97)00056-7" @default.
• W2092133552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9408205" @default.
• W2092133552 hasPublicationYear "1997" @default.
• W2092133552 type Work @default.
• W2092133552 sameAs 2092133552 @default.
• W2092133552 citedByCount "1" @default.
• W2092133552 crossrefType "journal-article" @default.
• W2092133552 hasAuthorship W2092133552A5007463627 @default.
• W2092133552 hasAuthorship W2092133552A5020196911 @default.
• W2092133552 hasAuthorship W2092133552A5033588723 @default.
• W2092133552 hasAuthorship W2092133552A5037457003 @default.
• W2092133552 hasAuthorship W2092133552A5044926937 @default.
• W2092133552 hasAuthorship W2092133552A5049258088 @default.
• W2092133552 hasConcept C100691959 @default.
• W2092133552 hasConcept C126322002 @default.
• W2092133552 hasConcept C134018914 @default.
• W2092133552 hasConcept C148762608 @default.
• W2092133552 hasConcept C15744967 @default.
• W2092133552 hasConcept C169760540 @default.

• next