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- W2092134043 abstract "When chlorisondamine was infused i.v. into cats, stimulation of the preganglionic cervical nerve caused the appearance of two non-nicotinic responses of the nicitating membrane, designated the late response (LR) and the late, late response (LLR). The LR reached a maximum after a brief period of stimulation (10 sec) had been terminated, and was blocked by small i.v. doses of atropine. The component of the LR which occurred during a 10 sec period of stimulation was reduced or abolished by eserine, but the component that occurred after determination of the stimulation was potentiated. The LLR reached a maximum about 2 min after cessation of a 40 sec volley to the preganglionic nerve and was unaffected by pretreatment with atropine or eserine. Similar late responses of the nictitating membrane were observed with hexamethonium, mecamylamine, or desensitizing doses of nicotine. It is concluded that the LR results from activation of ganglionic muscarinic receptors, and the LLR results from a non-cholinergic stimulation of ganglionic neurons." @default.
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- W2092134043 date "1973-10-01" @default.
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- W2092134043 title "Non-nicotinic transmission during ganglionic block with chlorisondamine and nicotine" @default.
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- W2092134043 doi "https://doi.org/10.1016/0014-2999(73)90116-7" @default.
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