FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092134310> ?p ?o ?g. }

• W2092134310 abstract "Natural killer (NK) cells accumulate at the maternal–fetal interface in large numbers, but their exact roles in successful pregnancy remain poorly defined. Here, we provide evidence that T H 17 cells and local inflammation can occur at the maternal–fetal interface during natural allogenic pregnancies. We found that decidual NK cells promote immune tolerance and successful pregnancy by dampening inflammatory T H 17 cells via IFN-γ secreted by the CD56 bright CD27 + NK subset. This NK-cell–mediated regulatory response is lost in patients who experience recurrent spontaneous abortions, which results in a prominent T H 17 response and extensive local inflammation. This local inflammatory response further affects the regulatory function of NK cells, leading to the eventual loss of maternal-fetal tolerance. Thus, our data identify NK cells as key regulatory cells at the maternal–fetal interface by suppressing T H 17-mediated local inflammation." @default.
• W2092134310 created "2016-06-24" @default.
• W2092134310 creator A5008578743 @default.
• W2092134310 creator A5012198733 @default.
• W2092134310 creator A5041353057 @default.
• W2092134310 creator A5041607266 @default.
• W2092134310 creator A5047855374 @default.
• W2092134310 creator A5082411086 @default.
• W2092134310 creator A5083130438 @default.
• W2092134310 date "2012-12-27" @default.
• W2092134310 modified "2023-10-05" @default.
• W2092134310 title "Natural killer cells promote immune tolerance by regulating inflammatory T_H17 cells at the human maternal–fetal interface" @default.
• W2092134310 cites W1498159349 @default.
• W2092134310 cites W1536634124 @default.
• W2092134310 cites W1560092366 @default.
• W2092134310 cites W1585944187 @default.
• W2092134310 cites W1605118942 @default.
• W2092134310 cites W1635103958 @default.
• W2092134310 cites W1659820601 @default.
• W2092134310 cites W1852086252 @default.
• W2092134310 cites W1866069858 @default.
• W2092134310 cites W1897632974 @default.
• W2092134310 cites W1943593754 @default.
• W2092134310 cites W1963962536 @default.
• W2092134310 cites W1966315835 @default.
• W2092134310 cites W1972038191 @default.
• W2092134310 cites W1973905104 @default.
• W2092134310 cites W1976853389 @default.
• W2092134310 cites W1978615362 @default.
• W2092134310 cites W1983448585 @default.
• W2092134310 cites W1986606398 @default.
• W2092134310 cites W1987267883 @default.
• W2092134310 cites W1987628377 @default.
• W2092134310 cites W2001878549 @default.
• W2092134310 cites W2003435719 @default.
• W2092134310 cites W2003734135 @default.
• W2092134310 cites W2005992769 @default.
• W2092134310 cites W2010737442 @default.
• W2092134310 cites W2011559299 @default.
• W2092134310 cites W2015260577 @default.
• W2092134310 cites W2017353776 @default.
• W2092134310 cites W2017990099 @default.
• W2092134310 cites W2018020394 @default.
• W2092134310 cites W2020151812 @default.
• W2092134310 cites W2021998052 @default.
• W2092134310 cites W2024490058 @default.
• W2092134310 cites W2028369131 @default.
• W2092134310 cites W2031222013 @default.
• W2092134310 cites W2034145671 @default.
• W2092134310 cites W2061487594 @default.
• W2092134310 cites W2074520223 @default.
• W2092134310 cites W2081204410 @default.
• W2092134310 cites W2090727535 @default.
• W2092134310 cites W2091671016 @default.
• W2092134310 cites W2093060517 @default.
• W2092134310 cites W2097425822 @default.
• W2092134310 cites W2098494951 @default.
• W2092134310 cites W2099703022 @default.
• W2092134310 cites W2105101447 @default.
• W2092134310 cites W2107652077 @default.
• W2092134310 cites W2113465151 @default.
• W2092134310 cites W2115118216 @default.
• W2092134310 cites W2126892029 @default.
• W2092134310 cites W2137653739 @default.
• W2092134310 cites W2139802799 @default.
• W2092134310 cites W2141295972 @default.
• W2092134310 cites W2141675109 @default.
• W2092134310 cites W2146879458 @default.
• W2092134310 cites W2147838205 @default.
• W2092134310 cites W2155554490 @default.
• W2092134310 cites W2156353286 @default.
• W2092134310 cites W2160675434 @default.
• W2092134310 cites W2162646944 @default.
• W2092134310 cites W2164526800 @default.
• W2092134310 doi "https://doi.org/10.1073/pnas.1206322110" @default.
• W2092134310 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3549088" @default.
• W2092134310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23271808" @default.
• W2092134310 hasPublicationYear "2012" @default.
• W2092134310 type Work @default.
• W2092134310 sameAs 2092134310 @default.
• W2092134310 citedByCount "226" @default.
• W2092134310 countsByYear W20921343102013 @default.
• W2092134310 countsByYear W20921343102014 @default.
• W2092134310 countsByYear W20921343102015 @default.
• W2092134310 countsByYear W20921343102016 @default.
• W2092134310 countsByYear W20921343102017 @default.
• W2092134310 countsByYear W20921343102018 @default.
• W2092134310 countsByYear W20921343102019 @default.
• W2092134310 countsByYear W20921343102020 @default.
• W2092134310 countsByYear W20921343102021 @default.
• W2092134310 countsByYear W20921343102022 @default.
• W2092134310 countsByYear W20921343102023 @default.
• W2092134310 crossrefType "journal-article" @default.
• W2092134310 hasAuthorship W2092134310A5008578743 @default.
• W2092134310 hasAuthorship W2092134310A5012198733 @default.
• W2092134310 hasAuthorship W2092134310A5041353057 @default.
• W2092134310 hasAuthorship W2092134310A5041607266 @default.
• W2092134310 hasAuthorship W2092134310A5047855374 @default.
• W2092134310 hasAuthorship W2092134310A5082411086 @default.
• W2092134310 hasAuthorship W2092134310A5083130438 @default.

• next