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- W2092135958 abstract "N-(3,5-Dichlorophenyl)-2-cysteinylsuccinimide methyl ester hydrochloride (5) was prepared from N-(3,5-dichlorophenyl)maleimide (3) and cysteinyl methyl ester hydrochloride. Attempted neutralization of the cysteine conjugate salt with triethylamine resulted in spontaneous cyclization of 5 to form the more stable 2-(N-3,5-dichlorophenylcarbamoylmethyl)-5-carbomethoxy-1,4-thiazine- 3-one (6). Similar results might be expected in vivo should these metabolites of succinimides be formed." @default.
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- W2092135958 date "1988-03-01" @default.
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- W2092135958 title "Cyclization of a cysteine conjugate of<i>N</i>-(3,5-Dichlorophenyl)succinimide" @default.
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- W2092135958 doi "https://doi.org/10.1002/jhet.5570250242" @default.
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