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- W2092136927 abstract "1 The characteristics of the acetylcholine (ACh) release mechanism have been studied in the auditory cortex of rabbits on stimulation of the ipsilateral medial geniculate nucleus. 2 On stimulation of the medial geniculate nucleus the mean release of ACh from the auditory receiving cortex was 6.1 times the spontaneous release; the mean release from other parts of the cortex was 2.2 times the spontaneous release. 3 The frequency of stimulation most effective in evoking ACh release was found to be 10/sec. 4 Both the spontaneous and evoked release of ACh were reduced by 40–65% in the absence of calcium from the solution bathing the auditory cortex, and increased by 15–25% when the calcium concentration in the bathing solution was doubled. 5 The presence of low concentrations of magnesium in the fluid bathing the cortex was essential for the optimal release of ACh, but high magnesium concentrations lowered this release. 6 The presence of triethylcholine (TEC) in the fluid bathing the auditory cortex reduced both the spontaneous and evoked release of ACh. This reduction was reversed in the presence of choline. 7 The effects of calcium, magnesium and TEC on the ACh release mechanism in the cerebral cortex and at the neuromuscular junction are compared." @default.
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- W2092136927 date "1969-05-01" @default.
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- W2092136927 title "The characteristics of acetylcholine release mechanisms in the auditory cortex" @default.
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