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- W2092148873 abstract "Mother rats were either fedad libitum or undernourished for much of pregnancy and throughout lactation. Their offspring were cross-fostered at birth, such that the young were nutritionally deprived during only one period, either gestation or the suckling period. The growth and development of these rats were compared with those of rats from an earlier investigation which were fully fed or undernourished during both periods. Food restriction during gestation caused a 10% deficit in birth weight, but from the fifth postnatal day the growth rate was almost entirely determined by the postnatal nutritional regime. The effect of nutritional deprivation during gestation on reflex ontogeny and the development of physical features was negligible, while that of postnatal underfeeding was highly significant with respect to most characteristics maturing after day 10. Only the appearance of certain aspects of exploratory behaviour showed evidence of being retarded by gestational restriction. Nutrition during the suckling period was a major determinant of the frequency of upward responding in the open field. Balancing ability at 21 days tended to be impaired in rats underfed during the suckling period. The results are discussed in relation to the vulnerable period hypothesis of brain growth and development and its application to the human species." @default.
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- W2092148873 date "1971-10-01" @default.
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- W2092148873 title "Vulnerability of developing brain. VI. relative effects of foetal and early postnatal undernutrition on reflex ontogeny and development of behaviour in the rat" @default.
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- W2092148873 doi "https://doi.org/10.1016/0006-8993(71)90105-3" @default.
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