Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092183584> ?p ?o ?g. }
- W2092183584 endingPage "40" @default.
- W2092183584 startingPage "31" @default.
- W2092183584 abstract "The purpose of the present study was to determine whether modulation of the trigeminal spinal nucleus oralis (TSNO) neurons related to tooth-pulp (TP)-evoked jaw-opening reflex (JOR) after electrical stimulation of the sciatic nerve (SN) is mediated by the descending serotonergic (5-HT(3)) inhibitory system activated by inhibitory GABAergic interneurons. In 30 anesthetized rats, the activity of TSNO neurons (87.5%, 35/40) and all digastric muscle electromyograms (dEMG, n=30) in response to TP stimulation (at an intensity of 3.5 times the threshold for JOR) were inhibited by conditioning stimulation of the SN (5.0 mA x 0.5 ms, 1 Hz, conditioning-test intervals; 50 ms). The inhibitory effects were significantly attenuated after intravenous administration of the 5-HT(3) receptor antagonist ICS 205-930 (n=6). Using multibarrel electrodes, iontophoretic application of ICS 205-930 into the TSNO significantly reduced the SN stimulation-induced inhibition of TP-evoked TSNO neuronal excitation (n=6), and in the same neurons, iontophoretic application of the GABA(A) receptor antagonist bicuculline into the TSNO greatly inhibited their effect. On the other hand, we found the expression of 5-HT(3) receptor immunoreactive neurons in the TSNO. These results suggest that SN stimulation may activate the descending serotonergic (5-HT(3)) inhibitory system through activation of inhibitory GABAergic interneurons, which inhibit excitatory responses of the TSNO neurons to TP stimulation." @default.
- W2092183584 created "2016-06-24" @default.
- W2092183584 creator A5000025706 @default.
- W2092183584 creator A5015093309 @default.
- W2092183584 creator A5031180314 @default.
- W2092183584 creator A5046129908 @default.
- W2092183584 creator A5072006202 @default.
- W2092183584 date "2005-02-01" @default.
- W2092183584 modified "2023-09-26" @default.
- W2092183584 title "Tooth-pulp-evoked rostral spinal trigeminal nucleus neuron activity is inhibited by conditioning sciatic nerve stimulation in the rat: possible role of 5-HT3 receptor mediated GABAergic inhibition" @default.
- W2092183584 cites W1591703307 @default.
- W2092183584 cites W1966510219 @default.
- W2092183584 cites W1970499952 @default.
- W2092183584 cites W1974479321 @default.
- W2092183584 cites W1985748225 @default.
- W2092183584 cites W1989133677 @default.
- W2092183584 cites W1989720563 @default.
- W2092183584 cites W1993079273 @default.
- W2092183584 cites W1998077078 @default.
- W2092183584 cites W2002131365 @default.
- W2092183584 cites W2005269801 @default.
- W2092183584 cites W2005395166 @default.
- W2092183584 cites W2007150768 @default.
- W2092183584 cites W2012551672 @default.
- W2092183584 cites W2013815084 @default.
- W2092183584 cites W2018098412 @default.
- W2092183584 cites W2020599403 @default.
- W2092183584 cites W2030343705 @default.
- W2092183584 cites W2034512476 @default.
- W2092183584 cites W2038024944 @default.
- W2092183584 cites W2040807712 @default.
- W2092183584 cites W2053508243 @default.
- W2092183584 cites W2056917572 @default.
- W2092183584 cites W2059435666 @default.
- W2092183584 cites W2066191028 @default.
- W2092183584 cites W2071562618 @default.
- W2092183584 cites W2075763817 @default.
- W2092183584 cites W2075817252 @default.
- W2092183584 cites W2084912221 @default.
- W2092183584 cites W2086603818 @default.
- W2092183584 cites W2088380795 @default.
- W2092183584 cites W2089776296 @default.
- W2092183584 cites W2090420678 @default.
- W2092183584 cites W2138512124 @default.
- W2092183584 cites W2150239645 @default.
- W2092183584 cites W2152289858 @default.
- W2092183584 cites W2153292899 @default.
- W2092183584 cites W2169923097 @default.
- W2092183584 cites W2463828365 @default.
- W2092183584 doi "https://doi.org/10.1016/j.brainresbull.2004.11.006" @default.
- W2092183584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15680543" @default.
- W2092183584 hasPublicationYear "2005" @default.
- W2092183584 type Work @default.
- W2092183584 sameAs 2092183584 @default.
- W2092183584 citedByCount "10" @default.
- W2092183584 countsByYear W20921835842014 @default.
- W2092183584 countsByYear W20921835842016 @default.
- W2092183584 countsByYear W20921835842017 @default.
- W2092183584 countsByYear W20921835842020 @default.
- W2092183584 crossrefType "journal-article" @default.
- W2092183584 hasAuthorship W2092183584A5000025706 @default.
- W2092183584 hasAuthorship W2092183584A5015093309 @default.
- W2092183584 hasAuthorship W2092183584A5031180314 @default.
- W2092183584 hasAuthorship W2092183584A5046129908 @default.
- W2092183584 hasAuthorship W2092183584A5072006202 @default.
- W2092183584 hasConcept C112592302 @default.
- W2092183584 hasConcept C15490471 @default.
- W2092183584 hasConcept C168258287 @default.
- W2092183584 hasConcept C169760540 @default.
- W2092183584 hasConcept C170493617 @default.
- W2092183584 hasConcept C17077164 @default.
- W2092183584 hasConcept C185592680 @default.
- W2092183584 hasConcept C24998067 @default.
- W2092183584 hasConcept C2775864247 @default.
- W2092183584 hasConcept C2776700747 @default.
- W2092183584 hasConcept C2779177108 @default.
- W2092183584 hasConcept C2780763569 @default.
- W2092183584 hasConcept C37000724 @default.
- W2092183584 hasConcept C55493867 @default.
- W2092183584 hasConcept C86803240 @default.
- W2092183584 hasConceptScore W2092183584C112592302 @default.
- W2092183584 hasConceptScore W2092183584C15490471 @default.
- W2092183584 hasConceptScore W2092183584C168258287 @default.
- W2092183584 hasConceptScore W2092183584C169760540 @default.
- W2092183584 hasConceptScore W2092183584C170493617 @default.
- W2092183584 hasConceptScore W2092183584C17077164 @default.
- W2092183584 hasConceptScore W2092183584C185592680 @default.
- W2092183584 hasConceptScore W2092183584C24998067 @default.
- W2092183584 hasConceptScore W2092183584C2775864247 @default.
- W2092183584 hasConceptScore W2092183584C2776700747 @default.
- W2092183584 hasConceptScore W2092183584C2779177108 @default.
- W2092183584 hasConceptScore W2092183584C2780763569 @default.
- W2092183584 hasConceptScore W2092183584C37000724 @default.
- W2092183584 hasConceptScore W2092183584C55493867 @default.
- W2092183584 hasConceptScore W2092183584C86803240 @default.
- W2092183584 hasIssue "1" @default.
- W2092183584 hasLocation W20921835841 @default.
- W2092183584 hasLocation W20921835842 @default.