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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092183926> ?p ?o ?g. }

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• W2092183926 abstract "Lipopolysaccharide (LPS) induction of TNF‐α release is a central event in the pathophysiology of Gram‐negative bacterial septicaemia. Lung surfactant protein A (SP‐A) mediates pathogen/host cell interactions. Binding of SP‐A to Pseudomonas aeruginosa LPS and the effects of SP‐A with LPS or whole bacteria on buffy coat cells were investigated. SP‐A interacts with P. aeruginosa LPS in a concentration and calcium dependent manner, either through the lipid A portion of LPS or through another lectin/carbohydrate interaction. SP‐A decreased TNF‐α secretion induced by bacteria or LPS from buffy coat cells, in a concentration dependent manner." @default.
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• W2092183926 date "1998-10-16" @default.
• W2092183926 modified "2023-09-25" @default.
• W2092183926 title "Induction of TNF-α release from human buffy coat cells by<i>Pseudomonas aeruginosa</i>is reduced by lung surfactant protein A" @default.
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• W2092183926 doi "https://doi.org/10.1016/s0014-5793(98)01200-9" @default.
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