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- W2092200521 abstract "Abstract Diaminobenzidine is a mutagen and possible carcinogen which is widely used in microscopy. The disposal of unneeded bulk quantities and aged working solutions is a problem for many laboratories. A number of methods for the treatment of diaminobenzidine for safe disposal were evaluated. The methods tested were oxidation with potassium permanganate in sulfuric acid, treatment with hydrogen peroxide in the presence of horseradish peroxidase, treatment with sodium hypochlorite, and treatment with sodium nitrite and hypophosphorous acid. The methods were tested to see that the compound was completely degraded and that only nonmutagenic reaction mixtures were produced. Two methods can be recommended for general use: destruction using potassium permanganate or using hydrogen peroxide in the presence of horseradish peroxidase. These procedures can be used for diaminobenzidine in tris(hydroxymethyl) aminomethane or phosphate buffer or for bulk quantities. The diaminobenzidine is completely destroyed (less ..." @default.
- W2092200521 created "2016-06-24" @default.
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- W2092200521 date "1991-01-01" @default.
- W2092200521 modified "2023-09-25" @default.
- W2092200521 title "The Safe Disposal of Diaminobenzidine" @default.
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- W2092200521 doi "https://doi.org/10.1080/1047322x.1991.10387826" @default.
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