FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092203973> ?p ?o ?g. }

• W2092203973 endingPage "16851" @default.
• W2092203973 startingPage "16847" @default.
• W2092203973 abstract "The oscillator of the circadian clock of cyanobacteria is composed of three proteins, KaiA, KaiB, and KaiC, which together generate a self-sustained ∼24-h rhythm of phosphorylation of KaiC. The mechanism propelling this oscillator has remained elusive, however. We show that stacking interactions between the CI and CII rings of KaiC drive the transition from the phosphorylation-specific KaiC–KaiA interaction to the dephosphorylation-specific KaiC–KaiB interaction. We have identified the KaiB-binding site, which is on the CI domain. This site is hidden when CI domains are associated as a hexameric ring. However, stacking of the CI and CII rings exposes the KaiB-binding site. Because the clock output protein SasA also binds to CI and competes with KaiB for binding, ring stacking likely regulates clock output. We demonstrate that ADP can expose the KaiB-binding site in the absence of ring stacking, providing an explanation for how it can reset the clock." @default.
• W2092203973 created "2016-06-24" @default.
• W2092203973 creator A5012787671 @default.
• W2092203973 creator A5043553548 @default.
• W2092203973 creator A5055275467 @default.
• W2092203973 creator A5078148736 @default.
• W2092203973 date "2012-09-11" @default.
• W2092203973 modified "2023-10-15" @default.
• W2092203973 title "Rhythmic ring–ring stacking drives the circadian oscillator clockwise" @default.
• W2092203973 cites W1781155185 @default.
• W2092203973 cites W1849062677 @default.
• W2092203973 cites W1964121026 @default.
• W2092203973 cites W1980298516 @default.
• W2092203973 cites W1982102680 @default.
• W2092203973 cites W1986426155 @default.
• W2092203973 cites W1995755513 @default.
• W2092203973 cites W2000591846 @default.
• W2092203973 cites W2002468644 @default.
• W2092203973 cites W2014918426 @default.
• W2092203973 cites W2020411151 @default.
• W2092203973 cites W2035571475 @default.
• W2092203973 cites W2037147814 @default.
• W2092203973 cites W2038763999 @default.
• W2092203973 cites W2046741099 @default.
• W2092203973 cites W2064397441 @default.
• W2092203973 cites W2073390681 @default.
• W2092203973 cites W2074406811 @default.
• W2092203973 cites W2074856155 @default.
• W2092203973 cites W2078461833 @default.
• W2092203973 cites W2079808386 @default.
• W2092203973 cites W2082904244 @default.
• W2092203973 cites W2088500461 @default.
• W2092203973 cites W2090023254 @default.
• W2092203973 cites W2091719092 @default.
• W2092203973 cites W2092314404 @default.
• W2092203973 cites W2092947007 @default.
• W2092203973 cites W2098515048 @default.
• W2092203973 cites W2103238897 @default.
• W2092203973 cites W2111307342 @default.
• W2092203973 cites W2120934149 @default.
• W2092203973 cites W2132582054 @default.
• W2092203973 cites W2134128681 @default.
• W2092203973 cites W2137244330 @default.
• W2092203973 cites W2142533333 @default.
• W2092203973 cites W2152868594 @default.
• W2092203973 cites W2169821755 @default.
• W2092203973 cites W2170492136 @default.
• W2092203973 cites W384364580 @default.
• W2092203973 doi "https://doi.org/10.1073/pnas.1211508109" @default.
• W2092203973 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3479483" @default.
• W2092203973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22967510" @default.
• W2092203973 hasPublicationYear "2012" @default.
• W2092203973 type Work @default.
• W2092203973 sameAs 2092203973 @default.
• W2092203973 citedByCount "96" @default.
• W2092203973 countsByYear W20922039732012 @default.
• W2092203973 countsByYear W20922039732013 @default.
• W2092203973 countsByYear W20922039732014 @default.
• W2092203973 countsByYear W20922039732015 @default.
• W2092203973 countsByYear W20922039732016 @default.
• W2092203973 countsByYear W20922039732017 @default.
• W2092203973 countsByYear W20922039732018 @default.
• W2092203973 countsByYear W20922039732019 @default.
• W2092203973 countsByYear W20922039732020 @default.
• W2092203973 countsByYear W20922039732021 @default.
• W2092203973 countsByYear W20922039732022 @default.
• W2092203973 countsByYear W20922039732023 @default.
• W2092203973 crossrefType "journal-article" @default.
• W2092203973 hasAuthorship W2092203973A5012787671 @default.
• W2092203973 hasAuthorship W2092203973A5043553548 @default.
• W2092203973 hasAuthorship W2092203973A5055275467 @default.
• W2092203973 hasAuthorship W2092203973A5078148736 @default.
• W2092203973 hasBestOaLocation W20922039731 @default.
• W2092203973 hasConcept C11960822 @default.
• W2092203973 hasConcept C121446783 @default.
• W2092203973 hasConcept C12554922 @default.
• W2092203973 hasConcept C169760540 @default.
• W2092203973 hasConcept C178666793 @default.
• W2092203973 hasConcept C178790620 @default.
• W2092203973 hasConcept C181912034 @default.
• W2092203973 hasConcept C185592680 @default.
• W2092203973 hasConcept C2780378348 @default.
• W2092203973 hasConcept C33347731 @default.
• W2092203973 hasConcept C38606739 @default.
• W2092203973 hasConcept C8010536 @default.
• W2092203973 hasConcept C86803240 @default.
• W2092203973 hasConcept C95444343 @default.
• W2092203973 hasConceptScore W2092203973C11960822 @default.
• W2092203973 hasConceptScore W2092203973C121446783 @default.
• W2092203973 hasConceptScore W2092203973C12554922 @default.
• W2092203973 hasConceptScore W2092203973C169760540 @default.
• W2092203973 hasConceptScore W2092203973C178666793 @default.
• W2092203973 hasConceptScore W2092203973C178790620 @default.
• W2092203973 hasConceptScore W2092203973C181912034 @default.
• W2092203973 hasConceptScore W2092203973C185592680 @default.
• W2092203973 hasConceptScore W2092203973C2780378348 @default.
• W2092203973 hasConceptScore W2092203973C33347731 @default.
• W2092203973 hasConceptScore W2092203973C38606739 @default.

• next