FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092207098> ?p ?o ?g. }

• W2092207098 endingPage "147" @default.
• W2092207098 startingPage "139" @default.
• W2092207098 abstract "The high binding affinity and specificity of antibodies for a great variety of ligands has been widely exploited in structure-activity relationship studies of biomolecules and more recently in the development of new catalysts for several chemical reactions. It is assumed that antibodies generated against haptenic protease inhibitors would recognize both these haptens and the substrate of the model proteolytic reaction. We have produced antibodies against HIV PRp12 aspartyl protease substrate analogues, chemically modified at the scissile bond, Phe-Pro. Identical chemical modifications have been reported for related HIV protease inhibitors. We finally selected an anti-hapten monoclonal antibody that specifically recognized the substrate and those haptens with both the phenylalanyl side chain and the prolyl pyrrolidine ring. This selectivity of recognition suggests that such an antibody might mimic the catalytic site of the model protease." @default.
• W2092207098 created "2016-06-24" @default.
• W2092207098 creator A5017897665 @default.
• W2092207098 creator A5045938878 @default.
• W2092207098 creator A5067997838 @default.
• W2092207098 creator A5075787578 @default.
• W2092207098 creator A5076117174 @default.
• W2092207098 creator A5081250910 @default.
• W2092207098 creator A5091241758 @default.
• W2092207098 date "1994-08-01" @default.
• W2092207098 modified "2023-09-26" @default.
• W2092207098 title "Characterization of a monoclonal antibody produced in an attempt to mimic the active site of HIV aspartyl protease using haptens based on inhibitor models" @default.
• W2092207098 cites W1968146515 @default.
• W2092207098 cites W1970636675 @default.
• W2092207098 cites W1973829820 @default.
• W2092207098 cites W1978630091 @default.
• W2092207098 cites W2024690257 @default.
• W2092207098 cites W2034295165 @default.
• W2092207098 cites W2037695285 @default.
• W2092207098 cites W2038350697 @default.
• W2092207098 cites W2043582941 @default.
• W2092207098 cites W2044177417 @default.
• W2092207098 cites W2053410564 @default.
• W2092207098 cites W2055806371 @default.
• W2092207098 cites W2057515951 @default.
• W2092207098 cites W2067027623 @default.
• W2092207098 cites W2075688420 @default.
• W2092207098 cites W2075873332 @default.
• W2092207098 cites W2079769193 @default.
• W2092207098 cites W2080262432 @default.
• W2092207098 cites W2085318243 @default.
• W2092207098 cites W2088519860 @default.
• W2092207098 cites W2090305900 @default.
• W2092207098 cites W2090920284 @default.
• W2092207098 cites W2094643920 @default.
• W2092207098 cites W2123631149 @default.
• W2092207098 cites W2148404862 @default.
• W2092207098 cites W2167465587 @default.
• W2092207098 cites W2949745155 @default.
• W2092207098 doi "https://doi.org/10.1016/0022-1759(94)90293-3" @default.
• W2092207098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8046248" @default.
• W2092207098 hasPublicationYear "1994" @default.
• W2092207098 type Work @default.
• W2092207098 sameAs 2092207098 @default.
• W2092207098 citedByCount "3" @default.
• W2092207098 crossrefType "journal-article" @default.
• W2092207098 hasAuthorship W2092207098A5017897665 @default.
• W2092207098 hasAuthorship W2092207098A5045938878 @default.
• W2092207098 hasAuthorship W2092207098A5067997838 @default.
• W2092207098 hasAuthorship W2092207098A5075787578 @default.
• W2092207098 hasAuthorship W2092207098A5076117174 @default.
• W2092207098 hasAuthorship W2092207098A5081250910 @default.
• W2092207098 hasAuthorship W2092207098A5091241758 @default.
• W2092207098 hasConcept C159654299 @default.
• W2092207098 hasConcept C181199279 @default.
• W2092207098 hasConcept C185592680 @default.
• W2092207098 hasConcept C18903297 @default.
• W2092207098 hasConcept C203014093 @default.
• W2092207098 hasConcept C21951064 @default.
• W2092207098 hasConcept C2776714187 @default.
• W2092207098 hasConcept C2777289219 @default.
• W2092207098 hasConcept C2777583353 @default.
• W2092207098 hasConcept C2778851528 @default.
• W2092207098 hasConcept C29144244 @default.
• W2092207098 hasConcept C41183919 @default.
• W2092207098 hasConcept C542903549 @default.
• W2092207098 hasConcept C55493867 @default.
• W2092207098 hasConcept C71240020 @default.
• W2092207098 hasConcept C86803240 @default.
• W2092207098 hasConcept C87282627 @default.
• W2092207098 hasConceptScore W2092207098C159654299 @default.
• W2092207098 hasConceptScore W2092207098C181199279 @default.
• W2092207098 hasConceptScore W2092207098C185592680 @default.
• W2092207098 hasConceptScore W2092207098C18903297 @default.
• W2092207098 hasConceptScore W2092207098C203014093 @default.
• W2092207098 hasConceptScore W2092207098C21951064 @default.
• W2092207098 hasConceptScore W2092207098C2776714187 @default.
• W2092207098 hasConceptScore W2092207098C2777289219 @default.
• W2092207098 hasConceptScore W2092207098C2777583353 @default.
• W2092207098 hasConceptScore W2092207098C2778851528 @default.
• W2092207098 hasConceptScore W2092207098C29144244 @default.
• W2092207098 hasConceptScore W2092207098C41183919 @default.
• W2092207098 hasConceptScore W2092207098C542903549 @default.
• W2092207098 hasConceptScore W2092207098C55493867 @default.
• W2092207098 hasConceptScore W2092207098C71240020 @default.
• W2092207098 hasConceptScore W2092207098C86803240 @default.
• W2092207098 hasConceptScore W2092207098C87282627 @default.
• W2092207098 hasIssue "2" @default.
• W2092207098 hasLocation W20922070981 @default.
• W2092207098 hasLocation W20922070982 @default.
• W2092207098 hasOpenAccess W2092207098 @default.
• W2092207098 hasPrimaryLocation W20922070981 @default.
• W2092207098 hasRelatedWork W1969837595 @default.
• W2092207098 hasRelatedWork W2027569059 @default.
• W2092207098 hasRelatedWork W2033131456 @default.
• W2092207098 hasRelatedWork W2041208462 @default.
• W2092207098 hasRelatedWork W2049250591 @default.
• W2092207098 hasRelatedWork W2092207098 @default.

• next