Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092220867> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2092220867 endingPage "194" @default.
- W2092220867 startingPage "187" @default.
- W2092220867 abstract "An endopeptidase generating fragment (1-5) from luteinizing hormone-releasing hormone (LHRH) has been solublized with Brij 35 from neuroblastoma cell membrane and purified by a procedure including p-mercuribenzoate-Sepharose chromatography, Mono-Q high-performance liquid chromatography and Superose 6 gel filtration. The molecular weight of the enzyme was estimated to be 100,000 by gel filtration. LHRH fragment (1-5)-generating activity of the enzyme was strongly inhibited by metal-chelating and sulfhydryl-blocking reagents. An enzyme with similar properties to those of the neuroblastoma enzyme was also purified from rat brain synaptic membranes. The properties of the two purified enzymes corresponded to those of a thiol-dependent protease proposed to be the enzyme responsible for the initial cleavage of LHRH by neuroblastoma cell membranes and rat brain synaptic membranes." @default.
- W2092220867 created "2016-06-24" @default.
- W2092220867 creator A5026608718 @default.
- W2092220867 creator A5060396150 @default.
- W2092220867 creator A5074354518 @default.
- W2092220867 creator A5078683191 @default.
- W2092220867 date "1990-08-01" @default.
- W2092220867 modified "2023-10-14" @default.
- W2092220867 title "Thiol-dependent membrane-bound metallo-endopeptidase functioning in degradation of luteinizing hormone-releasing hormone in neuroblastoma cells and rat brain synaptic membrane. Isolation and characterization" @default.
- W2092220867 cites W1854377422 @default.
- W2092220867 cites W1966053638 @default.
- W2092220867 cites W1976857150 @default.
- W2092220867 cites W2002775774 @default.
- W2092220867 cites W2023982600 @default.
- W2092220867 cites W2061105607 @default.
- W2092220867 cites W2069997087 @default.
- W2092220867 cites W2119567350 @default.
- W2092220867 cites W2408011942 @default.
- W2092220867 cites W4293247451 @default.
- W2092220867 doi "https://doi.org/10.1016/0143-4179(90)90061-3" @default.
- W2092220867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2177163" @default.
- W2092220867 hasPublicationYear "1990" @default.
- W2092220867 type Work @default.
- W2092220867 sameAs 2092220867 @default.
- W2092220867 citedByCount "4" @default.
- W2092220867 crossrefType "journal-article" @default.
- W2092220867 hasAuthorship W2092220867A5026608718 @default.
- W2092220867 hasAuthorship W2092220867A5060396150 @default.
- W2092220867 hasAuthorship W2092220867A5074354518 @default.
- W2092220867 hasAuthorship W2092220867A5078683191 @default.
- W2092220867 hasConcept C179247698 @default.
- W2092220867 hasConcept C181199279 @default.
- W2092220867 hasConcept C185592680 @default.
- W2092220867 hasConcept C193363816 @default.
- W2092220867 hasConcept C2777774944 @default.
- W2092220867 hasConcept C2779881004 @default.
- W2092220867 hasConcept C41625074 @default.
- W2092220867 hasConcept C43617362 @default.
- W2092220867 hasConcept C55493867 @default.
- W2092220867 hasConceptScore W2092220867C179247698 @default.
- W2092220867 hasConceptScore W2092220867C181199279 @default.
- W2092220867 hasConceptScore W2092220867C185592680 @default.
- W2092220867 hasConceptScore W2092220867C193363816 @default.
- W2092220867 hasConceptScore W2092220867C2777774944 @default.
- W2092220867 hasConceptScore W2092220867C2779881004 @default.
- W2092220867 hasConceptScore W2092220867C41625074 @default.
- W2092220867 hasConceptScore W2092220867C43617362 @default.
- W2092220867 hasConceptScore W2092220867C55493867 @default.
- W2092220867 hasIssue "4" @default.
- W2092220867 hasLocation W20922208671 @default.
- W2092220867 hasLocation W20922208672 @default.
- W2092220867 hasOpenAccess W2092220867 @default.
- W2092220867 hasPrimaryLocation W20922208671 @default.
- W2092220867 hasRelatedWork W1536108422 @default.
- W2092220867 hasRelatedWork W1906411624 @default.
- W2092220867 hasRelatedWork W1972107437 @default.
- W2092220867 hasRelatedWork W1978208898 @default.
- W2092220867 hasRelatedWork W2026465494 @default.
- W2092220867 hasRelatedWork W2043727313 @default.
- W2092220867 hasRelatedWork W2076636492 @default.
- W2092220867 hasRelatedWork W2328014763 @default.
- W2092220867 hasRelatedWork W2369453125 @default.
- W2092220867 hasRelatedWork W2376885290 @default.
- W2092220867 hasVolume "16" @default.
- W2092220867 isParatext "false" @default.
- W2092220867 isRetracted "false" @default.
- W2092220867 magId "2092220867" @default.
- W2092220867 workType "article" @default.