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- W2092247063 abstract "Reply: We thank Drs Basude and Dhawan for their comments. We agree that, had liver enzymes been measured before minocycline treatment was started, our patient's clinical picture would be clearer. One purpose of our report (1) was to alert clinicians to the possible clinical consequences of minocycline therapy and the importance of monitoring liver enzymes in patients receiving minocycline. Our patient's clinical course, including his positive anti-histone antibodies, is most typical of drug-induced liver disease. Other investigators have described patients with minocycline-induced liver disease who have required prolonged immunosuppressive therapy (2), similar to our patient. Although minocycline may cause autoimmune hepatitis, it may only do so in susceptible individuals. Differentiating between spontaneous autoimmune hepatitis and minocycline-induced autoimmune hepatitis in a child who has received minocycline may not be possible." @default.
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- W2092247063 date "2007-03-01" @default.
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- W2092247063 title "Authors' Response to Letter" @default.
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- W2092247063 doi "https://doi.org/10.1097/mpg.0b013e31802ec262" @default.
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