FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092248843> ?p ?o ?g. }

• W2092248843 endingPage "1589" @default.
• W2092248843 startingPage "1579" @default.
• W2092248843 abstract "—Choline acetyltransferase was extracted from Lactobacillus plantarum by relatively gentle procedures involving penicillin treatment, osmotic shock and passage through a French pressure cell. After partial purification, the extract was compared with choline acetyltransferase of calf caudate nucleus for kinetic properties and response to a class of inhibitors which consists of analogues of styrylpyridine. Both enzymes obeyed a sequential mechanism with Michaelis constants for the bacterial enzyme, Km= 8 μm vs. acetyl-CoA and 0·44 mm vs. choline; and for the caudate nucleus enzyme, Km= 15 μm vs. acetyl-CoA and 0·8 mm vs. choline. Both were stabilized by dithiothreitol and EDTA. The extracts differed in that the bacterial enzyme was more labile and apparently was susceptible to conformational changes, which modified its response to the styrylpyridinetype inhibitors. The use of intact cells of Lactobacillus plantarum as an in vivo system for studying the inhibition of choline acetyltransferase by styrylpyridines was possible only for non-quaternary analogues, which exist as an equilibrium mixture of charged and uncharged species." @default.
• W2092248843 created "2016-06-24" @default.
• W2092248843 creator A5068984828 @default.
• W2092248843 creator A5084317249 @default.
• W2092248843 date "1970-11-01" @default.
• W2092248843 modified "2023-09-25" @default.
• W2092248843 title "INHIBITION OF BACTERIAL AND MAMMALIAN CHOLINE ACETYLTRANSFERASES BY STYRYLPYRIDINE ANALOGUES" @default.
• W2092248843 cites W115017139 @default.
• W2092248843 cites W1543819219 @default.
• W2092248843 cites W1549849683 @default.
• W2092248843 cites W1622099522 @default.
• W2092248843 cites W1775749144 @default.
• W2092248843 cites W1966750067 @default.
• W2092248843 cites W1970014969 @default.
• W2092248843 cites W1972471279 @default.
• W2092248843 cites W1985407124 @default.
• W2092248843 cites W1992558157 @default.
• W2092248843 cites W1996342534 @default.
• W2092248843 cites W2000322970 @default.
• W2092248843 cites W2011876851 @default.
• W2092248843 cites W2030365597 @default.
• W2092248843 cites W2050961523 @default.
• W2092248843 cites W2062978587 @default.
• W2092248843 cites W2078513967 @default.
• W2092248843 cites W2083945806 @default.
• W2092248843 cites W2136506108 @default.
• W2092248843 cites W2408777832 @default.
• W2092248843 doi "https://doi.org/10.1111/j.1471-4159.1970.tb03728.x" @default.
• W2092248843 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5474659" @default.
• W2092248843 hasPublicationYear "1970" @default.
• W2092248843 type Work @default.
• W2092248843 sameAs 2092248843 @default.
• W2092248843 citedByCount "63" @default.
• W2092248843 countsByYear W20922488432016 @default.
• W2092248843 crossrefType "journal-article" @default.
• W2092248843 hasAuthorship W2092248843A5068984828 @default.
• W2092248843 hasAuthorship W2092248843A5084317249 @default.
• W2092248843 hasConcept C104317684 @default.
• W2092248843 hasConcept C119157956 @default.
• W2092248843 hasConcept C134018914 @default.
• W2092248843 hasConcept C150903083 @default.
• W2092248843 hasConcept C181199279 @default.
• W2092248843 hasConcept C185592680 @default.
• W2092248843 hasConcept C198399640 @default.
• W2092248843 hasConcept C207001950 @default.
• W2092248843 hasConcept C2775910092 @default.
• W2092248843 hasConcept C2775920511 @default.
• W2092248843 hasConcept C2777824588 @default.
• W2092248843 hasConcept C2778985185 @default.
• W2092248843 hasConcept C2779649592 @default.
• W2092248843 hasConcept C2781123555 @default.
• W2092248843 hasConcept C2781423529 @default.
• W2092248843 hasConcept C523546767 @default.
• W2092248843 hasConcept C54355233 @default.
• W2092248843 hasConcept C55493867 @default.
• W2092248843 hasConcept C71240020 @default.
• W2092248843 hasConcept C86803240 @default.
• W2092248843 hasConcept C98274493 @default.
• W2092248843 hasConceptScore W2092248843C104317684 @default.
• W2092248843 hasConceptScore W2092248843C119157956 @default.
• W2092248843 hasConceptScore W2092248843C134018914 @default.
• W2092248843 hasConceptScore W2092248843C150903083 @default.
• W2092248843 hasConceptScore W2092248843C181199279 @default.
• W2092248843 hasConceptScore W2092248843C185592680 @default.
• W2092248843 hasConceptScore W2092248843C198399640 @default.
• W2092248843 hasConceptScore W2092248843C207001950 @default.
• W2092248843 hasConceptScore W2092248843C2775910092 @default.
• W2092248843 hasConceptScore W2092248843C2775920511 @default.
• W2092248843 hasConceptScore W2092248843C2777824588 @default.
• W2092248843 hasConceptScore W2092248843C2778985185 @default.
• W2092248843 hasConceptScore W2092248843C2779649592 @default.
• W2092248843 hasConceptScore W2092248843C2781123555 @default.
• W2092248843 hasConceptScore W2092248843C2781423529 @default.
• W2092248843 hasConceptScore W2092248843C523546767 @default.
• W2092248843 hasConceptScore W2092248843C54355233 @default.
• W2092248843 hasConceptScore W2092248843C55493867 @default.
• W2092248843 hasConceptScore W2092248843C71240020 @default.
• W2092248843 hasConceptScore W2092248843C86803240 @default.
• W2092248843 hasConceptScore W2092248843C98274493 @default.
• W2092248843 hasIssue "11" @default.
• W2092248843 hasLocation W20922488431 @default.
• W2092248843 hasLocation W20922488432 @default.
• W2092248843 hasOpenAccess W2092248843 @default.
• W2092248843 hasPrimaryLocation W20922488431 @default.
• W2092248843 hasRelatedWork W1923163402 @default.
• W2092248843 hasRelatedWork W1986211337 @default.
• W2092248843 hasRelatedWork W1998321259 @default.
• W2092248843 hasRelatedWork W2035684545 @default.
• W2092248843 hasRelatedWork W2050961523 @default.
• W2092248843 hasRelatedWork W2061987904 @default.
• W2092248843 hasRelatedWork W2080353092 @default.
• W2092248843 hasRelatedWork W2080716683 @default.
• W2092248843 hasRelatedWork W2092248843 @default.
• W2092248843 hasRelatedWork W2414058774 @default.
• W2092248843 hasVolume "17" @default.
• W2092248843 isParatext "false" @default.
• W2092248843 isRetracted "false" @default.
• W2092248843 magId "2092248843" @default.

• next