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- W2092250290 endingPage "286" @default.
- W2092250290 startingPage "255" @default.
- W2092250290 abstract "The following macrolide antibiotics have been covered in this review: erythromycin and its related substances, azithromycin, clarithromycin, dirithromycin, roxithromycin, flurithromycin, josamycin, rokitamycin, kitasamycin, mycinamycin, mirosamycin, oleandomycin, rosaramicin, spiramycin and tylosin. The application of various thin-layer chromatography, paper chromatography, gas chromatography, high-performance liquid chromatography and capillary zone electrophoresis procedures for their analysis are described. These techniques have been applied to the separation and quantitative analysis of the macrolides in fermentation media, purity assessment of raw materials, assay of pharmaceutical dosage forms and the measurement of clinically useful macrolide antibiotics in biological samples such as blood, plasma, serum, urine and tissues. Data relating to the chromatographic behaviour of some macrolide antibiotics as well as the various detection methods used, such as bioautography, UV spectrophotometry, fluorometry, electrochemical detection, chemiluminescence and mass spectrometry techniques are also included." @default.
- W2092250290 created "2016-06-24" @default.
- W2092250290 creator A5013250837 @default.
- W2092250290 creator A5078464335 @default.
- W2092250290 creator A5080330665 @default.
- W2092250290 date "1998-07-01" @default.
- W2092250290 modified "2023-10-08" @default.
- W2092250290 title "Analysis of macrolide antibiotics" @default.
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