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- W2092256749 abstract "The differentiation of intoxication courses is one of the most difficult challenges for forensic pathologists and toxicologists. The case of a 52-year-old female inpatient of a psychiatric clinic with multiple medications who died from doxepin intoxication is reported. Concentrations of doxepin metabolites and isomers, pharmacokinetic modelling and genotyping of the doxepin-metabolizing cytochrome P450 (CYP) enzymes led to the following conclusion: the lethal doxepin concentration of 2100 ng/mL was more likely to have been reached due to drug interactions and genetic peculiarities leading to a reduction of the metabolic capacity and not by an acute (suicidal) overdose." @default.
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- W2092256749 date "2013-04-01" @default.
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- W2092256749 title "Fatal doxepin intoxication – Suicide or slow gradual intoxication?" @default.
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- W2092256749 doi "https://doi.org/10.1016/j.forsciint.2012.08.050" @default.
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