Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092289140> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2092289140 endingPage "5943" @default.
- W2092289140 startingPage "5939" @default.
- W2092289140 abstract "Treatment of rabbits, rats, and mice with D-galactosamine increased their sensitivity to the lethal effects of lipopolysaccharide several thousand fold. The susceptibility of the animals was highest when the lipopolysaccharide was injected together with galactosamine and decreased successively when injection was carried out 1, 2, and 3 hr later. Sensitization was absent when the lipopolysaccharide was administered 1 hr before or 4 hr after galactosamine. The onset of lethality after treatment with galactosamine and lipopolysaccharide occurred faster than with lipopolysaccharide alone; usually all animals died 5-9 hr later. The galactosamine-induced sensitization to lipopolysaccharide could be reversed by uridine which is known to inhibit the early biochemical alterations induced by the amino sugar in the hepatocytes. Although galactosamine is known to exhibit hepatotoxic activity inducing ultimate necrosis of the hepatocytes, the data so far suggests that the sensitization to lipopolysaccharide is related only to the early metabolic effects of the hexosamine." @default.
- W2092289140 created "2016-06-24" @default.
- W2092289140 creator A5032586373 @default.
- W2092289140 creator A5041935615 @default.
- W2092289140 creator A5086936229 @default.
- W2092289140 date "1979-11-01" @default.
- W2092289140 modified "2023-09-26" @default.
- W2092289140 title "Galactosamine-induced sensitization to the lethal effects of endotoxin." @default.
- W2092289140 cites W1503060625 @default.
- W2092289140 cites W1973887423 @default.
- W2092289140 cites W1992379349 @default.
- W2092289140 cites W2041505579 @default.
- W2092289140 cites W2114835627 @default.
- W2092289140 cites W2333166543 @default.
- W2092289140 cites W2913643801 @default.
- W2092289140 cites W342442057 @default.
- W2092289140 cites W384075993 @default.
- W2092289140 cites W88292867 @default.
- W2092289140 doi "https://doi.org/10.1073/pnas.76.11.5939" @default.
- W2092289140 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/411768" @default.
- W2092289140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/293694" @default.
- W2092289140 hasPublicationYear "1979" @default.
- W2092289140 type Work @default.
- W2092289140 sameAs 2092289140 @default.
- W2092289140 citedByCount "879" @default.
- W2092289140 countsByYear W20922891402012 @default.
- W2092289140 countsByYear W20922891402013 @default.
- W2092289140 countsByYear W20922891402014 @default.
- W2092289140 countsByYear W20922891402015 @default.
- W2092289140 countsByYear W20922891402016 @default.
- W2092289140 countsByYear W20922891402017 @default.
- W2092289140 countsByYear W20922891402018 @default.
- W2092289140 countsByYear W20922891402019 @default.
- W2092289140 countsByYear W20922891402020 @default.
- W2092289140 countsByYear W20922891402021 @default.
- W2092289140 countsByYear W20922891402022 @default.
- W2092289140 countsByYear W20922891402023 @default.
- W2092289140 crossrefType "journal-article" @default.
- W2092289140 hasAuthorship W2092289140A5032586373 @default.
- W2092289140 hasAuthorship W2092289140A5041935615 @default.
- W2092289140 hasAuthorship W2092289140A5086936229 @default.
- W2092289140 hasBestOaLocation W20922891402 @default.
- W2092289140 hasConcept C126322002 @default.
- W2092289140 hasConcept C185592680 @default.
- W2092289140 hasConcept C203014093 @default.
- W2092289140 hasConcept C2776217527 @default.
- W2092289140 hasConcept C2778125326 @default.
- W2092289140 hasConcept C2778754761 @default.
- W2092289140 hasConcept C2781467277 @default.
- W2092289140 hasConcept C55493867 @default.
- W2092289140 hasConcept C71924100 @default.
- W2092289140 hasConcept C98274493 @default.
- W2092289140 hasConceptScore W2092289140C126322002 @default.
- W2092289140 hasConceptScore W2092289140C185592680 @default.
- W2092289140 hasConceptScore W2092289140C203014093 @default.
- W2092289140 hasConceptScore W2092289140C2776217527 @default.
- W2092289140 hasConceptScore W2092289140C2778125326 @default.
- W2092289140 hasConceptScore W2092289140C2778754761 @default.
- W2092289140 hasConceptScore W2092289140C2781467277 @default.
- W2092289140 hasConceptScore W2092289140C55493867 @default.
- W2092289140 hasConceptScore W2092289140C71924100 @default.
- W2092289140 hasConceptScore W2092289140C98274493 @default.
- W2092289140 hasIssue "11" @default.
- W2092289140 hasLocation W20922891401 @default.
- W2092289140 hasLocation W20922891402 @default.
- W2092289140 hasLocation W20922891403 @default.
- W2092289140 hasLocation W20922891404 @default.
- W2092289140 hasOpenAccess W2092289140 @default.
- W2092289140 hasPrimaryLocation W20922891401 @default.
- W2092289140 hasRelatedWork W1480461322 @default.
- W2092289140 hasRelatedWork W1812663661 @default.
- W2092289140 hasRelatedWork W1962480635 @default.
- W2092289140 hasRelatedWork W2013570523 @default.
- W2092289140 hasRelatedWork W2014426957 @default.
- W2092289140 hasRelatedWork W2092289140 @default.
- W2092289140 hasRelatedWork W2144847280 @default.
- W2092289140 hasRelatedWork W2523496983 @default.
- W2092289140 hasRelatedWork W3116192584 @default.
- W2092289140 hasRelatedWork W2181861283 @default.
- W2092289140 hasVolume "76" @default.
- W2092289140 isParatext "false" @default.
- W2092289140 isRetracted "false" @default.
- W2092289140 magId "2092289140" @default.
- W2092289140 workType "article" @default.