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• W2092294828 abstract "The inhibition effects of enantiomerically pure α-(N-benzylamino)benzylphosphonic acids and their derivatives on human prostatic acid phosphatase have been investigated. As expected, (R)-α-(N-benzylamino)benzylphosphonic acid demonstrated higher affinity for the enzyme than (S)-enantiomer. At the same time, (1R,2S)-phenyl[(1-phenylethyl)amino]methylphosphonic acid was found to be a significantly weaker inhibitor than its (1S,2R)-analogue. The enantioselectivity has been explained using a molecular modeling approach by computational docking of inhibitors into active center of prostatic acid phosphatase." @default.
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• W2092294828 date "2008-08-01" @default.
• W2092294828 modified "2023-10-07" @default.
• W2092294828 title "Stereoselectivity of binding of α-(N-benzylamino)benzylphosphonic acids to prostatic acid phosphatase" @default.
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• W2092294828 doi "https://doi.org/10.1016/j.bmcl.2008.07.021" @default.
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