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• W2092366048 abstract "Objective To assess effects of a cognitively based program on health-related behaviors and cardiovascular risk factors in overweight drug-treated hypertensives. Study Design and Setting In a clinical trials center, volunteers, recruited by advertisement, were randomized to usual care (N=118) or to a 4-month program (N=123) incorporating weight loss; a low-sodium diet, high in fruit, vegetables, and fish; and increased physical activity. Diet, physical activity, weight, blood lipids, glucose, and insulin were measured at 4 and 16 months. Results Ninety-eight usual care and 106 program participants completed the 4-month assessment; 90 and 102, respectively, completed follow-up. Using intention-to-treat analysis, relative to usual care, net changes with the program at 4 months were as follows: dietary fat (−2.6% energy; P<0.001); sodium (−290 mg/d; P=0.004); energy (−313 mJ/d; P=0.005); fish (+2.1 serves/wk; P<0.001); vegetables (+3.0 serves/wk; P<0.001); physical activity (+37 min/wk; P=0.004); weight (−2.8 kg; P<0.001); waist girth (−3.1 cm; P<0.001); total cholesterol (−0.2 mmol/L; P=0.017); and triacylglycerols (−0.12 mmol/L; P=0.002). One year later, net changes included dietary fat (−2.2% energy; P<0.001); sodium (−150 mg/d; P=0.029); fish (+2.0 serves/wk; P<0.001); vegetables (+4.3 serves/wk; P<0.001); weight (−2.5 kg; P=0.001); waist girth (−3.1 cm; P<0.001); high-density lipoprotein cholesterol (+0.03 mmol/L; P=0.031). Conclusion Improvements in behaviors and risk factors, several maintained long term, suggest the potential for long-term benefits in hypertensives." @default.
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• W2092366048 date "2007-02-01" @default.
• W2092366048 modified "2023-10-18" @default.
• W2092366048 title "A lifestyle program for treated hypertensives improved health-related behaviors and cardiovascular risk factors, a randomized controlled trial" @default.
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• W2092366048 doi "https://doi.org/10.1016/j.jclinepi.2006.05.012" @default.
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