FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092370086> ?p ?o ?g. }

• W2092370086 endingPage "433" @default.
• W2092370086 startingPage "422" @default.
• W2092370086 abstract "The purpose of this study is to determine dose delivery errors that could result from random and systematic setup errors for head-and-neck patients treated using the simultaneous integrated boost (SIB)-intensity-modulated radiation therapy (IMRT) technique.Twenty-four patients who participated in an intramural Phase I/II parotid-sparing IMRT dose-escalation protocol using the SIB treatment technique had their dose distributions reevaluated to assess the impact of random and systematic setup errors. The dosimetric effect of random setup error was simulated by convolving the two-dimensional fluence distribution of each beam with the random setup error probability density distribution. Random setup errors of sigma = 1, 3, and 5 mm were simulated. Systematic setup errors were simulated by randomly shifting the patient isocenter along each of the three Cartesian axes, with each shift selected from a normal distribution. Systematic setup error distributions with Sigma = 1.5 and 3.0 mm along each axis were simulated. Combined systematic and random setup errors were simulated for sigma = Sigma = 1.5 and 3.0 mm along each axis. For each dose calculation, the gross tumor volume (GTV) received by 98% of the volume (D(98)), clinical target volume (CTV) D(90), nodes D(90), cord D(2), and parotid D(50) and parotid mean dose were evaluated with respect to the plan used for treatment for the structure dose and for an effective planning target volume (PTV) with a 3-mm margin.Simultaneous integrated boost-IMRT head-and-neck treatment plans were found to be less sensitive to random setup errors than to systematic setup errors. For random-only errors, errors exceeded 3% only when the random setup error sigma exceeded 3 mm. Simulated systematic setup errors with Sigma = 1.5 mm resulted in approximately 10% of plan having more than a 3% dose error, whereas a Sigma = 3.0 mm resulted in half of the plans having more than a 3% dose error and 28% with a 5% dose error. Combined random and systematic dose errors with sigma = Sigma = 3.0 mm resulted in more than 50% of plans having at least a 3% dose error and 38% of the plans having at least a 5% dose error. Evaluation with respect to a 3-mm expanded PTV reduced the observed dose deviations greater than 5% for the sigma = Sigma = 3.0 mm simulations to 5.4% of the plans simulated.Head-and-neck SIB-IMRT dosimetric accuracy would benefit from methods to reduce patient systematic setup errors. When GTV, CTV, or nodal volumes are used for dose evaluation, plans simulated including the effects of random and systematic errors deviate substantially from the nominal plan. The use of PTVs for dose evaluation in the nominal plan improves agreement with evaluated GTV, CTV, and nodal dose values under simulated setup errors. PTV concepts should be used for SIB-IMRT head-and-neck squamous cell carcinoma patients, although the size of the margins may be less than those used with three-dimensional conformal radiation therapy." @default.
• W2092370086 created "2016-06-24" @default.
• W2092370086 creator A5005969181 @default.
• W2092370086 creator A5012356605 @default.
• W2092370086 creator A5015195004 @default.
• W2092370086 creator A5032752677 @default.
• W2092370086 creator A5069570157 @default.
• W2092370086 date "2005-10-01" @default.
• W2092370086 modified "2023-09-30" @default.
• W2092370086 title "Effect of patient setup errors on simultaneously integrated boost head and neck IMRT treatment plans" @default.
• W2092370086 cites W1966709141 @default.
• W2092370086 cites W1966890696 @default.
• W2092370086 cites W1977764193 @default.
• W2092370086 cites W1983273276 @default.
• W2092370086 cites W1997613975 @default.
• W2092370086 cites W2008906982 @default.
• W2092370086 cites W2015687286 @default.
• W2092370086 cites W2019226981 @default.
• W2092370086 cites W2019774627 @default.
• W2092370086 cites W2023302702 @default.
• W2092370086 cites W2030023766 @default.
• W2092370086 cites W2054946224 @default.
• W2092370086 cites W2060436037 @default.
• W2092370086 cites W2061234057 @default.
• W2092370086 cites W2063265874 @default.
• W2092370086 cites W2066557915 @default.
• W2092370086 cites W2077252581 @default.
• W2092370086 cites W2080972692 @default.
• W2092370086 cites W2083629503 @default.
• W2092370086 cites W2084674759 @default.
• W2092370086 cites W2085796495 @default.
• W2092370086 cites W2090688261 @default.
• W2092370086 cites W2091608575 @default.
• W2092370086 cites W2104383911 @default.
• W2092370086 cites W2111273332 @default.
• W2092370086 cites W2122062060 @default.
• W2092370086 cites W2125947698 @default.
• W2092370086 cites W2126680055 @default.
• W2092370086 cites W2141695199 @default.
• W2092370086 cites W2160901318 @default.
• W2092370086 cites W2170080153 @default.
• W2092370086 cites W2355419393 @default.
• W2092370086 cites W278452154 @default.
• W2092370086 doi "https://doi.org/10.1016/j.ijrobp.2005.02.029" @default.
• W2092370086 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16168835" @default.
• W2092370086 hasPublicationYear "2005" @default.
• W2092370086 type Work @default.
• W2092370086 sameAs 2092370086 @default.
• W2092370086 citedByCount "79" @default.
• W2092370086 countsByYear W20923700862012 @default.
• W2092370086 countsByYear W20923700862013 @default.
• W2092370086 countsByYear W20923700862014 @default.
• W2092370086 countsByYear W20923700862015 @default.
• W2092370086 countsByYear W20923700862016 @default.
• W2092370086 countsByYear W20923700862017 @default.
• W2092370086 countsByYear W20923700862018 @default.
• W2092370086 countsByYear W20923700862019 @default.
• W2092370086 countsByYear W20923700862020 @default.
• W2092370086 countsByYear W20923700862021 @default.
• W2092370086 countsByYear W20923700862022 @default.
• W2092370086 countsByYear W20923700862023 @default.
• W2092370086 crossrefType "journal-article" @default.
• W2092370086 hasAuthorship W2092370086A5005969181 @default.
• W2092370086 hasAuthorship W2092370086A5012356605 @default.
• W2092370086 hasAuthorship W2092370086A5015195004 @default.
• W2092370086 hasAuthorship W2092370086A5032752677 @default.
• W2092370086 hasAuthorship W2092370086A5069570157 @default.
• W2092370086 hasBestOaLocation W20923700861 @default.
• W2092370086 hasConcept C104293457 @default.
• W2092370086 hasConcept C105795698 @default.
• W2092370086 hasConcept C126838900 @default.
• W2092370086 hasConcept C181401712 @default.
• W2092370086 hasConcept C201645570 @default.
• W2092370086 hasConcept C2989005 @default.
• W2092370086 hasConcept C33923547 @default.
• W2092370086 hasConcept C509974204 @default.
• W2092370086 hasConcept C71924100 @default.
• W2092370086 hasConcept C73782692 @default.
• W2092370086 hasConceptScore W2092370086C104293457 @default.
• W2092370086 hasConceptScore W2092370086C105795698 @default.
• W2092370086 hasConceptScore W2092370086C126838900 @default.
• W2092370086 hasConceptScore W2092370086C181401712 @default.
• W2092370086 hasConceptScore W2092370086C201645570 @default.
• W2092370086 hasConceptScore W2092370086C2989005 @default.
• W2092370086 hasConceptScore W2092370086C33923547 @default.
• W2092370086 hasConceptScore W2092370086C509974204 @default.
• W2092370086 hasConceptScore W2092370086C71924100 @default.
• W2092370086 hasConceptScore W2092370086C73782692 @default.
• W2092370086 hasIssue "2" @default.
• W2092370086 hasLocation W20923700861 @default.
• W2092370086 hasLocation W20923700862 @default.
• W2092370086 hasOpenAccess W2092370086 @default.
• W2092370086 hasPrimaryLocation W20923700861 @default.
• W2092370086 hasRelatedWork W1997611269 @default.
• W2092370086 hasRelatedWork W2007249268 @default.
• W2092370086 hasRelatedWork W2048241981 @default.
• W2092370086 hasRelatedWork W2088088656 @default.
• W2092370086 hasRelatedWork W2129285699 @default.

• next