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- W2092379828 abstract "In a recent publication (DeLisi et al 1992) we reported data showing no significant ventricular enlargement or temporal lobe volume reduction in 50 schizophreniform patients compared with controls. As a result, we concluded that either there was a progressive component to the degree of ventficular enlargement detected in chronic patients, or patients with a first hospitalization for schizophreniform disorder (who tend to be functioning well until < 6 months prior to hospitalization) are not the subgroup of schizophrenic patients who have significant brain pathology. Though these explanations cannot yet be ruled out, a third, equally important one was overlooked; that is, only a portion of schizopbreniform patients (those with less than. 6 months of symptoms) may be destined to be diagnosed as definite schizophrenia with time, ~.d thus only a smaller proportion of the 50 p~ti¢~ts may be expected to have ventricular enlargement than would be seen if a similar sample of schizophrenic subjects of longer illness :lu~:atioa were studied. Thus, the overall difle:ences in the schizophreniform group as a whole may not be significantly different from controls. However, if the initial scans of those that were later di-" @default.
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- W2092379828 date "1992-07-01" @default.
- W2092379828 modified "2023-10-16" @default.
- W2092379828 title "Left ventricular enlargement associated with diagnostic outcome of schizophreniform disorder" @default.
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- W2092379828 doi "https://doi.org/10.1016/0006-3223(92)90025-u" @default.
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