Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092384346> ?p ?o ?g. }
- W2092384346 endingPage "e63627" @default.
- W2092384346 startingPage "e63627" @default.
- W2092384346 abstract "Transthyretin (TTR) is a known carrier protein for thyroxine (T4) and retinol-binding protein in the blood that is primarily synthesized in the liver and choroid plexus of the brain. Herein, we report that the TTR gene is expressed in skeletal muscle tissue and up-regulated during myotube formation in C2C12 cells. TTR silencing (TTRkd) significantly reduced myogenin expression and myotube formation, whereas myogenin silencing (MYOGkd) did not have any effect on TTR gene expression. Both TTRkd and MYOGkd led to a decrease in calcium channel related genes including Cav1.1, STIM1 and Orai1. A significant decrease in intracellular T4 uptake during myogenesis was observed in TTRkd cells. Taken together, the results of this study suggest that TTR initiates myoblast differentiation via affecting expression of the genes involved during early stage of myogenesis and the genes related to calcium channel." @default.
- W2092384346 created "2016-06-24" @default.
- W2092384346 creator A5012365258 @default.
- W2092384346 creator A5019666497 @default.
- W2092384346 creator A5020182388 @default.
- W2092384346 creator A5026921085 @default.
- W2092384346 creator A5029552326 @default.
- W2092384346 creator A5037580192 @default.
- W2092384346 creator A5042452147 @default.
- W2092384346 creator A5046444973 @default.
- W2092384346 creator A5047082339 @default.
- W2092384346 creator A5049406319 @default.
- W2092384346 creator A5068729851 @default.
- W2092384346 creator A5068881816 @default.
- W2092384346 creator A5078717180 @default.
- W2092384346 date "2013-05-22" @default.
- W2092384346 modified "2023-10-18" @default.
- W2092384346 title "Transthyretin Is a Key Regulator of Myoblast Differentiation" @default.
- W2092384346 cites W1858595724 @default.
- W2092384346 cites W1878905851 @default.
- W2092384346 cites W1888485870 @default.
- W2092384346 cites W1912505476 @default.
- W2092384346 cites W1971760726 @default.
- W2092384346 cites W1973953525 @default.
- W2092384346 cites W1987013513 @default.
- W2092384346 cites W1991988594 @default.
- W2092384346 cites W2002615785 @default.
- W2092384346 cites W2004751759 @default.
- W2092384346 cites W2014497336 @default.
- W2092384346 cites W2015219413 @default.
- W2092384346 cites W2017429680 @default.
- W2092384346 cites W2019544139 @default.
- W2092384346 cites W2022223340 @default.
- W2092384346 cites W2026004506 @default.
- W2092384346 cites W2028190732 @default.
- W2092384346 cites W2031330996 @default.
- W2092384346 cites W2036503829 @default.
- W2092384346 cites W2042326040 @default.
- W2092384346 cites W2049515855 @default.
- W2092384346 cites W2053047024 @default.
- W2092384346 cites W2053907473 @default.
- W2092384346 cites W2066389308 @default.
- W2092384346 cites W2068800778 @default.
- W2092384346 cites W2069778993 @default.
- W2092384346 cites W2069989784 @default.
- W2092384346 cites W2072957984 @default.
- W2092384346 cites W2075009214 @default.
- W2092384346 cites W2075173841 @default.
- W2092384346 cites W2081544530 @default.
- W2092384346 cites W2084746444 @default.
- W2092384346 cites W2090840497 @default.
- W2092384346 cites W2096701787 @default.
- W2092384346 cites W2108671981 @default.
- W2092384346 cites W2121628947 @default.
- W2092384346 cites W2125885007 @default.
- W2092384346 cites W2146376634 @default.
- W2092384346 cites W2148736421 @default.
- W2092384346 cites W2163794476 @default.
- W2092384346 cites W4293247451 @default.
- W2092384346 doi "https://doi.org/10.1371/journal.pone.0063627" @default.
- W2092384346 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3661549" @default.
- W2092384346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23717457" @default.
- W2092384346 hasPublicationYear "2013" @default.
- W2092384346 type Work @default.
- W2092384346 sameAs 2092384346 @default.
- W2092384346 citedByCount "17" @default.
- W2092384346 countsByYear W20923843462014 @default.
- W2092384346 countsByYear W20923843462015 @default.
- W2092384346 countsByYear W20923843462016 @default.
- W2092384346 countsByYear W20923843462017 @default.
- W2092384346 countsByYear W20923843462019 @default.
- W2092384346 countsByYear W20923843462020 @default.
- W2092384346 countsByYear W20923843462021 @default.
- W2092384346 crossrefType "journal-article" @default.
- W2092384346 hasAuthorship W2092384346A5012365258 @default.
- W2092384346 hasAuthorship W2092384346A5019666497 @default.
- W2092384346 hasAuthorship W2092384346A5020182388 @default.
- W2092384346 hasAuthorship W2092384346A5026921085 @default.
- W2092384346 hasAuthorship W2092384346A5029552326 @default.
- W2092384346 hasAuthorship W2092384346A5037580192 @default.
- W2092384346 hasAuthorship W2092384346A5042452147 @default.
- W2092384346 hasAuthorship W2092384346A5046444973 @default.
- W2092384346 hasAuthorship W2092384346A5047082339 @default.
- W2092384346 hasAuthorship W2092384346A5049406319 @default.
- W2092384346 hasAuthorship W2092384346A5068729851 @default.
- W2092384346 hasAuthorship W2092384346A5068881816 @default.
- W2092384346 hasAuthorship W2092384346A5078717180 @default.
- W2092384346 hasBestOaLocation W20923843461 @default.
- W2092384346 hasConcept C104317684 @default.
- W2092384346 hasConcept C119056186 @default.
- W2092384346 hasConcept C121157162 @default.
- W2092384346 hasConcept C134018914 @default.
- W2092384346 hasConcept C153911025 @default.
- W2092384346 hasConcept C207200792 @default.
- W2092384346 hasConcept C2779959927 @default.
- W2092384346 hasConcept C3763915 @default.
- W2092384346 hasConcept C54355233 @default.
- W2092384346 hasConcept C60278653 @default.