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- W2092394230 abstract "1.The extent of phenformin absorption and its rate of urinary excretion have been assessed in adult patients with iron deficiency anaemia, a condition which compromises gastrointestinal function.2.Phenformin (100 mg) was administered orally to patients before treatment, three days after the start of a course of iron treatment (oral 300 mg b.d. or total intravenous iron) and at the end of 28 days, when haemoglobin was over 10 gm%.3.No significant difference was found between mean total amounts of phenformin and 4-hydroxyphenformin excreted in urine, before treatment or after 3 or 28 days replacement therapy. It is concluded that phenformin absorption is not affected by iron deficiency.4.In addition, iron deficiency had no significant effect on phenformin elimination half-life." @default.
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- W2092394230 date "1988-01-01" @default.
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- W2092394230 title "Effect of iron deficiency anaemia and its treatment on the absorption and elimination of phenformin" @default.
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- W2092394230 doi "https://doi.org/10.3109/00498258809042241" @default.
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