FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092406095> ?p ?o ?g. }

• W2092406095 endingPage "844" @default.
• W2092406095 startingPage "835" @default.
• W2092406095 abstract "Encephalitis has many causes, but for most patients the cause is unknown. We aimed to establish the cause and identify the clinical differences between causes in patients with encephalitis in England.Patients of all ages and with symptoms suggestive of encephalitis were actively recruited for 2 years (staged start between October, 2005, and November, 2006) from 24 hospitals by clinical staff. Systematic laboratory testing included PCR and antibody assays for all commonly recognised causes of infectious encephalitis, investigation for less commonly recognised causes in immunocompromised patients, and testing for travel-related causes if indicated. We also tested for non-infectious causes for acute encephalitis including autoimmunity. A multidisciplinary expert team reviewed clinical presentation and hospital tests and directed further investigations. Patients were followed up for 6 months after discharge from hospital.We identified 203 patients with encephalitis. Median age was 30 years (range 0-87). 86 patients (42%, 95% CI 35-49) had infectious causes, including 38 (19%, 14-25) herpes simplex virus, ten (5%, 2-9) varicella zoster virus, and ten (5%, 2-9) Mycobacterium tuberculosis; 75 (37%, 30-44) had unknown causes. 42 patients (21%, 15-27) had acute immune-mediated encephalitis. 24 patients (12%, 8-17) died, with higher case fatality for infections from M tuberculosis (three patients; 30%, 7-65) and varicella zoster virus (two patients; 20%, 2-56). The 16 patients with antibody-associated encephalitis had the worst outcome of all groups-nine (56%, 30-80) either died or had severe disabilities. Patients who died were more likely to be immunocompromised than were those who survived (OR = 3·44).Early diagnosis of encephalitis is crucial to ensure that the right treatment is given on time. Extensive testing substantially reduced the proportion with unknown cause, but the proportion of cases with unknown cause was higher than that for any specific identified cause.The Policy Research Programme, Department of Health, UK." @default.
• W2092406095 created "2016-06-24" @default.
• W2092406095 creator A5005306517 @default.
• W2092406095 creator A5005748460 @default.
• W2092406095 creator A5008592726 @default.
• W2092406095 creator A5011628620 @default.
• W2092406095 creator A5012005202 @default.
• W2092406095 creator A5023555465 @default.
• W2092406095 creator A5029359449 @default.
• W2092406095 creator A5045704773 @default.
• W2092406095 creator A5046263207 @default.
• W2092406095 creator A5050764672 @default.
• W2092406095 creator A5052940001 @default.
• W2092406095 creator A5062939642 @default.
• W2092406095 creator A5067780933 @default.
• W2092406095 creator A5071194530 @default.
• W2092406095 creator A5073669305 @default.
• W2092406095 creator A5077595049 @default.
• W2092406095 date "2010-12-01" @default.
• W2092406095 modified "2023-10-17" @default.
• W2092406095 title "Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study" @default.
• W2092406095 cites W1874700596 @default.
• W2092406095 cites W1964649969 @default.
• W2092406095 cites W1973647109 @default.
• W2092406095 cites W1977179445 @default.
• W2092406095 cites W2004775359 @default.
• W2092406095 cites W2006051718 @default.
• W2092406095 cites W2006795308 @default.
• W2092406095 cites W2009802670 @default.
• W2092406095 cites W2032049067 @default.
• W2092406095 cites W2047312613 @default.
• W2092406095 cites W2058022954 @default.
• W2092406095 cites W2065557665 @default.
• W2092406095 cites W2077934868 @default.
• W2092406095 cites W2087363103 @default.
• W2092406095 cites W2105600079 @default.
• W2092406095 cites W2118067546 @default.
• W2092406095 cites W2121799179 @default.
• W2092406095 cites W2126835932 @default.
• W2092406095 cites W2131625303 @default.
• W2092406095 cites W2133197143 @default.
• W2092406095 cites W2137311953 @default.
• W2092406095 cites W2146199022 @default.
• W2092406095 cites W2149150328 @default.
• W2092406095 cites W2149239333 @default.
• W2092406095 cites W2149507482 @default.
• W2092406095 cites W2154286617 @default.
• W2092406095 cites W2155108682 @default.
• W2092406095 cites W2169075035 @default.
• W2092406095 cites W2336900894 @default.
• W2092406095 cites W4239341883 @default.
• W2092406095 cites W4299631805 @default.
• W2092406095 cites W54703682 @default.
• W2092406095 doi "https://doi.org/10.1016/s1473-3099(10)70222-x" @default.
• W2092406095 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20952256" @default.
• W2092406095 hasPublicationYear "2010" @default.
• W2092406095 type Work @default.
• W2092406095 sameAs 2092406095 @default.
• W2092406095 citedByCount "1023" @default.
• W2092406095 countsByYear W20924060952012 @default.
• W2092406095 countsByYear W20924060952013 @default.
• W2092406095 countsByYear W20924060952014 @default.
• W2092406095 countsByYear W20924060952015 @default.
• W2092406095 countsByYear W20924060952016 @default.
• W2092406095 countsByYear W20924060952017 @default.
• W2092406095 countsByYear W20924060952018 @default.
• W2092406095 countsByYear W20924060952019 @default.
• W2092406095 countsByYear W20924060952020 @default.
• W2092406095 countsByYear W20924060952021 @default.
• W2092406095 countsByYear W20924060952022 @default.
• W2092406095 countsByYear W20924060952023 @default.
• W2092406095 crossrefType "journal-article" @default.
• W2092406095 hasAuthorship W2092406095A5005306517 @default.
• W2092406095 hasAuthorship W2092406095A5005748460 @default.
• W2092406095 hasAuthorship W2092406095A5008592726 @default.
• W2092406095 hasAuthorship W2092406095A5011628620 @default.
• W2092406095 hasAuthorship W2092406095A5012005202 @default.
• W2092406095 hasAuthorship W2092406095A5023555465 @default.
• W2092406095 hasAuthorship W2092406095A5029359449 @default.
• W2092406095 hasAuthorship W2092406095A5045704773 @default.
• W2092406095 hasAuthorship W2092406095A5046263207 @default.
• W2092406095 hasAuthorship W2092406095A5050764672 @default.
• W2092406095 hasAuthorship W2092406095A5052940001 @default.
• W2092406095 hasAuthorship W2092406095A5062939642 @default.
• W2092406095 hasAuthorship W2092406095A5067780933 @default.
• W2092406095 hasAuthorship W2092406095A5071194530 @default.
• W2092406095 hasAuthorship W2092406095A5073669305 @default.
• W2092406095 hasAuthorship W2092406095A5077595049 @default.
• W2092406095 hasBestOaLocation W20924060951 @default.
• W2092406095 hasConcept C107130276 @default.
• W2092406095 hasConcept C126322002 @default.
• W2092406095 hasConcept C142724271 @default.
• W2092406095 hasConcept C187212893 @default.
• W2092406095 hasConcept C187316915 @default.
• W2092406095 hasConcept C203014093 @default.
• W2092406095 hasConcept C2522874641 @default.
• W2092406095 hasConcept C2776159415 @default.
• W2092406095 hasConcept C2779141303 @default.

• next