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- W2092448675 abstract "This study assessed selective dermal rejuvenation using sequential intradermal injections of carbon dioxide and hyaluronic acid as a treatment of facial wrinkles. An injection device was designed. After topical anesthesia, 0.1-mL carbon dioxide was gently injected intradermally so as to spread diffusely. A volume of 0.01- to 0.02-mL diluted hyaluronic acid was sequentially injected until the skin rose slightly. Overlapping injections were performed at 3 to 5 mm intervals. This process was repeated until the wrinkles were smoothened. This study included 36 cases of facial wrinkles in 34 patients. The follow-up period was 3 to 11 months. Temporary adverse effects were injection-site pain, mild edema, and redness. Most cases showed obvious improvement in skin thickness, elasticity, and smoothening. Complications included irregularities and hyperpigmentation in 3 cases, and 91% were highly satisfied with the antiwrinkle treatment. This method was a safe, economical, and clinically effective antiwrinkle treatment." @default.
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- W2092448675 date "2013-06-01" @default.
- W2092448675 modified "2023-09-24" @default.
- W2092448675 title "Selective Dermal Rejuvenation Using Intradermal Injection of Carbon Dioxide and Hyaluronic Acid for Facial Wrinkles" @default.
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- W2092448675 doi "https://doi.org/10.1097/sap.0b013e31823fa958" @default.
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