Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092458500> ?p ?o ?g. }
- W2092458500 endingPage "885" @default.
- W2092458500 startingPage "879" @default.
- W2092458500 abstract "In Brief BACKGROUND: Several studies have addressed the expression of transient receptor potential vanilloid subfamily 1(TRPV1) playing an important role in the generation of cancer pain. Electroacupuncture (EA) is an effective method of acupuncture shown to attenuate different kinds of pain such as inflammatory, neuropathic, and cancer. In this study, we investigated the effect of EA on cancer pain caused by intraplantar injection of Walker 256 carcinoma cells and cancer-driven TRPV1 expression in the dorsal root ganglions (DRGs). METHODS: Rats were randomly divided into 4 groups: the nontumor cell inoculation group (normal control, n = 8); Walker 256 carcinoma cell inoculation group (tumor control, n = 8); sham point electrical stimulation treatment with Walker 256 carcinoma cell inoculation group (SES, n = 8); EA treatment with Walker 256 carcinoma cell inoculation group (EA, n = 8). The time courses of thermal, mechanical sensitivity, and spontaneous nocifensive behavior were determined. In addition, TRPV1 expression in DRGs was observed by quantitative real-time polymerase chain reaction and Western blotting. RESULTS: Injection of cancer cells decreased the paw withdrawal threshold, increased spontaneous nocifensive behavior, and induced significant thermal hyperalgesia that was attenuated by EA at the ST36 acupoint (2 Hz, 0.3 ms, ≤1 mA). TRPV1 mRNA and protein in DRGs were upregulated in the cancer pain model, and EA at ST36 acupoint counteracted the cancer-driven upregulation of TRPV1 expression in the corresponding DRGs. CONCLUSIONS: EA at ST36 could attenuate cancer-induced pain, at least in part, through suppressing TRPV1 mRNA and protein upregulation in the DRGs. Published ahead of print January 16, 2012" @default.
- W2092458500 created "2016-06-24" @default.
- W2092458500 creator A5002840699 @default.
- W2092458500 creator A5003088149 @default.
- W2092458500 creator A5013509380 @default.
- W2092458500 creator A5014617619 @default.
- W2092458500 creator A5030691366 @default.
- W2092458500 creator A5058275202 @default.
- W2092458500 creator A5075700545 @default.
- W2092458500 creator A5083757203 @default.
- W2092458500 date "2012-04-01" @default.
- W2092458500 modified "2023-09-28" @default.
- W2092458500 title "The Effects of Electroacupuncture at the ST36 (Zusanli) Acupoint on Cancer Pain and Transient Receptor Potential Vanilloid Subfamily 1 Expression in Walker 256 Tumor-Bearing Rats" @default.
- W2092458500 cites W1498513766 @default.
- W2092458500 cites W1511198581 @default.
- W2092458500 cites W1970446666 @default.
- W2092458500 cites W1973528953 @default.
- W2092458500 cites W1974620224 @default.
- W2092458500 cites W1977480987 @default.
- W2092458500 cites W1988011642 @default.
- W2092458500 cites W1992144394 @default.
- W2092458500 cites W1997379737 @default.
- W2092458500 cites W2002459373 @default.
- W2092458500 cites W2006726845 @default.
- W2092458500 cites W2007891803 @default.
- W2092458500 cites W2008648558 @default.
- W2092458500 cites W2012071423 @default.
- W2092458500 cites W2016097366 @default.
- W2092458500 cites W2038372590 @default.
- W2092458500 cites W2041060509 @default.
- W2092458500 cites W2042465203 @default.
- W2092458500 cites W2049140862 @default.
- W2092458500 cites W2051192926 @default.
- W2092458500 cites W2061479000 @default.
- W2092458500 cites W2071357102 @default.
- W2092458500 cites W2071503561 @default.
- W2092458500 cites W2074268464 @default.
- W2092458500 cites W2075653731 @default.
- W2092458500 cites W2081891742 @default.
- W2092458500 cites W2088916591 @default.
- W2092458500 cites W2092891148 @default.
- W2092458500 cites W2094323079 @default.
- W2092458500 cites W2095235718 @default.
- W2092458500 cites W2098374383 @default.
- W2092458500 cites W2100789450 @default.
- W2092458500 cites W2104656246 @default.
- W2092458500 cites W2116863239 @default.
- W2092458500 cites W2119457185 @default.
- W2092458500 cites W2128690456 @default.
- W2092458500 cites W2131398498 @default.
- W2092458500 cites W2142793826 @default.
- W2092458500 cites W2144862641 @default.
- W2092458500 cites W2149085099 @default.
- W2092458500 cites W2159301559 @default.
- W2092458500 cites W2165178937 @default.
- W2092458500 cites W2166861626 @default.
- W2092458500 cites W2323620710 @default.
- W2092458500 doi "https://doi.org/10.1213/ane.0b013e318246536d" @default.
- W2092458500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22253272" @default.
- W2092458500 hasPublicationYear "2012" @default.
- W2092458500 type Work @default.
- W2092458500 sameAs 2092458500 @default.
- W2092458500 citedByCount "43" @default.
- W2092458500 countsByYear W20924585002012 @default.
- W2092458500 countsByYear W20924585002013 @default.
- W2092458500 countsByYear W20924585002014 @default.
- W2092458500 countsByYear W20924585002015 @default.
- W2092458500 countsByYear W20924585002016 @default.
- W2092458500 countsByYear W20924585002017 @default.
- W2092458500 countsByYear W20924585002018 @default.
- W2092458500 countsByYear W20924585002019 @default.
- W2092458500 countsByYear W20924585002020 @default.
- W2092458500 countsByYear W20924585002021 @default.
- W2092458500 countsByYear W20924585002022 @default.
- W2092458500 countsByYear W20924585002023 @default.
- W2092458500 crossrefType "journal-article" @default.
- W2092458500 hasAuthorship W2092458500A5002840699 @default.
- W2092458500 hasAuthorship W2092458500A5003088149 @default.
- W2092458500 hasAuthorship W2092458500A5013509380 @default.
- W2092458500 hasAuthorship W2092458500A5014617619 @default.
- W2092458500 hasAuthorship W2092458500A5030691366 @default.
- W2092458500 hasAuthorship W2092458500A5058275202 @default.
- W2092458500 hasAuthorship W2092458500A5075700545 @default.
- W2092458500 hasAuthorship W2092458500A5083757203 @default.
- W2092458500 hasBestOaLocation W20924585001 @default.
- W2092458500 hasConcept C104317684 @default.
- W2092458500 hasConcept C121608353 @default.
- W2092458500 hasConcept C126322002 @default.
- W2092458500 hasConcept C127561419 @default.
- W2092458500 hasConcept C142724271 @default.
- W2092458500 hasConcept C155164980 @default.
- W2092458500 hasConcept C160145004 @default.
- W2092458500 hasConcept C170493617 @default.
- W2092458500 hasConcept C204787440 @default.
- W2092458500 hasConcept C2776202274 @default.
- W2092458500 hasConcept C2778904085 @default.
- W2092458500 hasConcept C2779504368 @default.
- W2092458500 hasConcept C42219234 @default.