FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092460012> ?p ?o ?g. }

• W2092460012 endingPage "485" @default.
• W2092460012 startingPage "477" @default.
• W2092460012 abstract "Isosmotical replacement of extracellular Na+ ([Na+]0) by K+, choline and to a lesser extent by saccharose stimulated the release of chorionic gonadotrophin and placental lactogen from human term placental explants. The effect of [Na+]0 removal on the release of both hormones was concentration-dependent and was inhibited in the absence of extracellular Ca2+ or in the presence of 0.5 mM Co2+, a Ca2+ entry blocker. Blockers of the voltage-sensitive Ca2+ channels (20μM nifedipine and 50μM methoxyverapamil) or Na+ channels (5μM tetrodotoxin) did not affect the stimulatory effects of [Na+]0 omission. By contrast, Mg2+ and Sr2+ (10 mM) as well as amiloride (2 mM) and its analogue 2′, 4′-dimethylbenzamil (50μm), all known to affect the Na+−Ca2+ exchange, markedly reduced the increase in hormone release elicited by [Na+]0 removal. Lastly, the secretory responses to [Na+]0 deprivation were increased in the presence of 2 mM ouabain, an inhibitor of the Na+−K+ ATPase. These results indicate for the first time that [Na+]0 omission provokes a Ca2+-dependent stimulation of human chorionic gonadotrophin and placental lactogen releases. The pharmacological dissection of the secretory effects of [Na+]0 removal supports the existence of a process of Na+−Ca2+ exchange in placental cells." @default.
• W2092460012 created "2016-06-24" @default.
• W2092460012 creator A5003213840 @default.
• W2092460012 creator A5035033819 @default.
• W2092460012 creator A5040689564 @default.
• W2092460012 creator A5051780150 @default.
• W2092460012 date "1994-07-01" @default.
• W2092460012 modified "2023-10-18" @default.
• W2092460012 title "The release of human chorionic gonadotrophin and placental lactogen by placental explants can be stimulated by Ca2+ entry through a Na+−Ca2+ exchange process" @default.
• W2092460012 cites W1583322461 @default.
• W2092460012 cites W1913357042 @default.
• W2092460012 cites W2000913970 @default.
• W2092460012 cites W2014190932 @default.
• W2092460012 cites W2014540285 @default.
• W2092460012 cites W2019176764 @default.
• W2092460012 cites W2022128427 @default.
• W2092460012 cites W2030781430 @default.
• W2092460012 cites W2054639283 @default.
• W2092460012 cites W2118929544 @default.
• W2092460012 cites W2123126335 @default.
• W2092460012 cites W2130105549 @default.
• W2092460012 cites W2137669857 @default.
• W2092460012 cites W2140513053 @default.
• W2092460012 cites W2268223071 @default.
• W2092460012 cites W2340537867 @default.
• W2092460012 cites W2921135897 @default.
• W2092460012 doi "https://doi.org/10.1016/s0143-4004(05)80417-5" @default.
• W2092460012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7997448" @default.
• W2092460012 hasPublicationYear "1994" @default.
• W2092460012 type Work @default.
• W2092460012 sameAs 2092460012 @default.
• W2092460012 citedByCount "9" @default.
• W2092460012 countsByYear W20924600122013 @default.
• W2092460012 crossrefType "journal-article" @default.
• W2092460012 hasAuthorship W2092460012A5003213840 @default.
• W2092460012 hasAuthorship W2092460012A5035033819 @default.
• W2092460012 hasAuthorship W2092460012A5040689564 @default.
• W2092460012 hasAuthorship W2092460012A5051780150 @default.
• W2092460012 hasConcept C126322002 @default.
• W2092460012 hasConcept C134018914 @default.
• W2092460012 hasConcept C153461711 @default.
• W2092460012 hasConcept C172680121 @default.
• W2092460012 hasConcept C178790620 @default.
• W2092460012 hasConcept C185592680 @default.
• W2092460012 hasConcept C24998067 @default.
• W2092460012 hasConcept C2776741303 @default.
• W2092460012 hasConcept C2776953305 @default.
• W2092460012 hasConcept C2777064457 @default.
• W2092460012 hasConcept C2779066535 @default.
• W2092460012 hasConcept C2779133857 @default.
• W2092460012 hasConcept C2779234561 @default.
• W2092460012 hasConcept C2779608910 @default.
• W2092460012 hasConcept C28406088 @default.
• W2092460012 hasConcept C519063684 @default.
• W2092460012 hasConcept C537181965 @default.
• W2092460012 hasConcept C54355233 @default.
• W2092460012 hasConcept C55493867 @default.
• W2092460012 hasConcept C71924100 @default.
• W2092460012 hasConcept C86803240 @default.
• W2092460012 hasConceptScore W2092460012C126322002 @default.
• W2092460012 hasConceptScore W2092460012C134018914 @default.
• W2092460012 hasConceptScore W2092460012C153461711 @default.
• W2092460012 hasConceptScore W2092460012C172680121 @default.
• W2092460012 hasConceptScore W2092460012C178790620 @default.
• W2092460012 hasConceptScore W2092460012C185592680 @default.
• W2092460012 hasConceptScore W2092460012C24998067 @default.
• W2092460012 hasConceptScore W2092460012C2776741303 @default.
• W2092460012 hasConceptScore W2092460012C2776953305 @default.
• W2092460012 hasConceptScore W2092460012C2777064457 @default.
• W2092460012 hasConceptScore W2092460012C2779066535 @default.
• W2092460012 hasConceptScore W2092460012C2779133857 @default.
• W2092460012 hasConceptScore W2092460012C2779234561 @default.
• W2092460012 hasConceptScore W2092460012C2779608910 @default.
• W2092460012 hasConceptScore W2092460012C28406088 @default.
• W2092460012 hasConceptScore W2092460012C519063684 @default.
• W2092460012 hasConceptScore W2092460012C537181965 @default.
• W2092460012 hasConceptScore W2092460012C54355233 @default.
• W2092460012 hasConceptScore W2092460012C55493867 @default.
• W2092460012 hasConceptScore W2092460012C71924100 @default.
• W2092460012 hasConceptScore W2092460012C86803240 @default.
• W2092460012 hasIssue "5" @default.
• W2092460012 hasLocation W20924600121 @default.
• W2092460012 hasLocation W20924600122 @default.
• W2092460012 hasOpenAccess W2092460012 @default.
• W2092460012 hasPrimaryLocation W20924600121 @default.
• W2092460012 hasRelatedWork W1991908139 @default.
• W2092460012 hasRelatedWork W2009158156 @default.
• W2092460012 hasRelatedWork W2031824119 @default.
• W2092460012 hasRelatedWork W2051945705 @default.
• W2092460012 hasRelatedWork W2053709222 @default.
• W2092460012 hasRelatedWork W2054992011 @default.
• W2092460012 hasRelatedWork W2064416809 @default.
• W2092460012 hasRelatedWork W2092460012 @default.
• W2092460012 hasRelatedWork W2094920468 @default.
• W2092460012 hasRelatedWork W2417802249 @default.
• W2092460012 hasVolume "15" @default.
• W2092460012 isParatext "false" @default.
• W2092460012 isRetracted "false" @default.

• next