FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092492011> ?p ?o ?g. }

• W2092492011 endingPage "34" @default.
• W2092492011 startingPage "25" @default.
• W2092492011 abstract "Abstract Latest research on biological systems is steadily shifting from isolated single cells to entire cell populations. The latter are inherently heterogeneous, and their modeling requires approaches that explicitly account for this property. A comprehensive such approach is the cell population balance (CPB), which, however, is computationally expensive and becomes intractable for multi-variable models. In this work, we demonstrate the use of model-reduction to efficiently simulate cell population heterogeneity in a genetic network of a single gene with feedback. Starting from a 4-species model, we use singular perturbation analysis to derive a single equation for the intracellular protein concentration. We subsequently incorporate this equation to a hybrid model consisting of a CPB for the cell volume, and a continuum equation for the protein concentration. We finally compare the results obtained with the hybrid model with those of the full CPB, demonstrating the accuracy and computational efficiency of the hybrid methodology." @default.
• W2092492011 created "2016-06-24" @default.
• W2092492011 creator A5081859091 @default.
• W2092492011 date "2013-06-01" @default.
• W2092492011 modified "2023-09-26" @default.
• W2092492011 title "Cell population balance and hybrid modeling of population dynamics for a single gene with feedback" @default.
• W2092492011 cites W1024343985 @default.
• W2092492011 cites W1587852390 @default.
• W2092492011 cites W1966011701 @default.
• W2092492011 cites W1967757831 @default.
• W2092492011 cites W1971534037 @default.
• W2092492011 cites W1980438352 @default.
• W2092492011 cites W1988676138 @default.
• W2092492011 cites W1991508286 @default.
• W2092492011 cites W2002115571 @default.
• W2092492011 cites W2007728693 @default.
• W2092492011 cites W2017859373 @default.
• W2092492011 cites W2019462270 @default.
• W2092492011 cites W2020668111 @default.
• W2092492011 cites W2022150802 @default.
• W2092492011 cites W2031900448 @default.
• W2092492011 cites W2032070954 @default.
• W2092492011 cites W2040431513 @default.
• W2092492011 cites W2041592362 @default.
• W2092492011 cites W2041687536 @default.
• W2092492011 cites W2046975114 @default.
• W2092492011 cites W2051698985 @default.
• W2092492011 cites W2071748580 @default.
• W2092492011 cites W2073796239 @default.
• W2092492011 cites W2075835338 @default.
• W2092492011 cites W2078782879 @default.
• W2092492011 cites W2090841507 @default.
• W2092492011 cites W2092961051 @default.
• W2092492011 cites W2094051182 @default.
• W2092492011 cites W2106097745 @default.
• W2092492011 cites W2107109081 @default.
• W2092492011 cites W2115098139 @default.
• W2092492011 cites W2131144426 @default.
• W2092492011 cites W2137018402 @default.
• W2092492011 cites W2137799314 @default.
• W2092492011 cites W2148386985 @default.
• W2092492011 cites W2149035803 @default.
• W2092492011 cites W2169693875 @default.
• W2092492011 cites W2770091082 @default.
• W2092492011 cites W4247623139 @default.
• W2092492011 doi "https://doi.org/10.1016/j.compchemeng.2013.02.006" @default.
• W2092492011 hasPublicationYear "2013" @default.
• W2092492011 type Work @default.
• W2092492011 sameAs 2092492011 @default.
• W2092492011 citedByCount "7" @default.
• W2092492011 countsByYear W20924920112014 @default.
• W2092492011 countsByYear W20924920112016 @default.
• W2092492011 countsByYear W20924920112017 @default.
• W2092492011 countsByYear W20924920112018 @default.
• W2092492011 crossrefType "journal-article" @default.
• W2092492011 hasAuthorship W2092492011A5081859091 @default.
• W2092492011 hasBestOaLocation W20924920112 @default.
• W2092492011 hasConcept C121332964 @default.
• W2092492011 hasConcept C145912823 @default.
• W2092492011 hasConcept C154945302 @default.
• W2092492011 hasConcept C168031717 @default.
• W2092492011 hasConcept C169760540 @default.
• W2092492011 hasConcept C186060115 @default.
• W2092492011 hasConcept C24890656 @default.
• W2092492011 hasConcept C2775924081 @default.
• W2092492011 hasConcept C2908647359 @default.
• W2092492011 hasConcept C41008148 @default.
• W2092492011 hasConcept C47446073 @default.
• W2092492011 hasConcept C71924100 @default.
• W2092492011 hasConcept C86803240 @default.
• W2092492011 hasConcept C99454951 @default.
• W2092492011 hasConceptScore W2092492011C121332964 @default.
• W2092492011 hasConceptScore W2092492011C145912823 @default.
• W2092492011 hasConceptScore W2092492011C154945302 @default.
• W2092492011 hasConceptScore W2092492011C168031717 @default.
• W2092492011 hasConceptScore W2092492011C169760540 @default.
• W2092492011 hasConceptScore W2092492011C186060115 @default.
• W2092492011 hasConceptScore W2092492011C24890656 @default.
• W2092492011 hasConceptScore W2092492011C2775924081 @default.
• W2092492011 hasConceptScore W2092492011C2908647359 @default.
• W2092492011 hasConceptScore W2092492011C41008148 @default.
• W2092492011 hasConceptScore W2092492011C47446073 @default.
• W2092492011 hasConceptScore W2092492011C71924100 @default.
• W2092492011 hasConceptScore W2092492011C86803240 @default.
• W2092492011 hasConceptScore W2092492011C99454951 @default.
• W2092492011 hasLocation W20924920111 @default.
• W2092492011 hasLocation W20924920112 @default.
• W2092492011 hasLocation W20924920113 @default.
• W2092492011 hasOpenAccess W2092492011 @default.
• W2092492011 hasPrimaryLocation W20924920111 @default.
• W2092492011 hasRelatedWork W1975388572 @default.
• W2092492011 hasRelatedWork W1997890493 @default.
• W2092492011 hasRelatedWork W2088062465 @default.
• W2092492011 hasRelatedWork W2152924178 @default.
• W2092492011 hasRelatedWork W2359941961 @default.
• W2092492011 hasRelatedWork W2365624195 @default.
• W2092492011 hasRelatedWork W2385394455 @default.
• W2092492011 hasRelatedWork W2906352773 @default.

• next