Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092505562> ?p ?o ?g. }
- W2092505562 endingPage "172" @default.
- W2092505562 startingPage "163" @default.
- W2092505562 abstract "We have screened the Eurofan deletion strain collection for mutants that are either sensitive or resistant to three drugs known to affect intracellular transport: brefeldin A, monensin and C2-ceramide. Drug-sensitive mutants were analysed by complementation with cognate clones and tetrad analysis to confirm that the phenotypes are linked to the deletions. Out of 620 deletion strains, we found 18 mutants that were sensitive to either brefeldin A, monensin or both. Several of these mutants are deleted for genes that are known to be involved in intracellular transport, membrane biogenesis and/or cell wall biosynthesis. Among such previously known genes were VAM6, VAC7, SYS1, TLG2, RCY1, ERG4, ALG9 and ALG12. Some other genes recovered in our screen were not previously implicated in intracellular transport, but are related to other yeast genes with such a function. Still other genes encode proteins with no obvious link to intracellular transport. Several of these are putative transcription factors or RNA-binding proteins, which suggests that they may affect drug sensitivity by modulating the expression of other genes or proteins. Copyright © 2000 John Wiley & Sons, Ltd." @default.
- W2092505562 created "2016-06-24" @default.
- W2092505562 creator A5009649673 @default.
- W2092505562 creator A5021095726 @default.
- W2092505562 creator A5049417333 @default.
- W2092505562 creator A5058279698 @default.
- W2092505562 date "2000-11-28" @default.
- W2092505562 modified "2023-10-05" @default.
- W2092505562 title "Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport" @default.
- W2092505562 cites W1508614407 @default.
- W2092505562 cites W1591600424 @default.
- W2092505562 cites W1654890776 @default.
- W2092505562 cites W1897417227 @default.
- W2092505562 cites W1938386297 @default.
- W2092505562 cites W1966446749 @default.
- W2092505562 cites W1968112541 @default.
- W2092505562 cites W1968633942 @default.
- W2092505562 cites W1971265845 @default.
- W2092505562 cites W1974652610 @default.
- W2092505562 cites W1983635742 @default.
- W2092505562 cites W1995254238 @default.
- W2092505562 cites W1998963313 @default.
- W2092505562 cites W2004705005 @default.
- W2092505562 cites W2005812143 @default.
- W2092505562 cites W2009644279 @default.
- W2092505562 cites W2010618201 @default.
- W2092505562 cites W2011590818 @default.
- W2092505562 cites W20155414 @default.
- W2092505562 cites W2020456066 @default.
- W2092505562 cites W2023578962 @default.
- W2092505562 cites W2028799740 @default.
- W2092505562 cites W2028967650 @default.
- W2092505562 cites W2033050778 @default.
- W2092505562 cites W2040649045 @default.
- W2092505562 cites W2048697340 @default.
- W2092505562 cites W2052887360 @default.
- W2092505562 cites W2056917962 @default.
- W2092505562 cites W2057703601 @default.
- W2092505562 cites W2059428912 @default.
- W2092505562 cites W2063238480 @default.
- W2092505562 cites W2070359951 @default.
- W2092505562 cites W2070614988 @default.
- W2092505562 cites W2073688200 @default.
- W2092505562 cites W2074286043 @default.
- W2092505562 cites W2077513922 @default.
- W2092505562 cites W2078245264 @default.
- W2092505562 cites W2078959581 @default.
- W2092505562 cites W2090374544 @default.
- W2092505562 cites W2090486711 @default.
- W2092505562 cites W2100057937 @default.
- W2092505562 cites W2101011430 @default.
- W2092505562 cites W2101219710 @default.
- W2092505562 cites W2104496647 @default.
- W2092505562 cites W2108157396 @default.
- W2092505562 cites W2112866008 @default.
- W2092505562 cites W2113343108 @default.
- W2092505562 cites W2114254051 @default.
- W2092505562 cites W2129828626 @default.
- W2092505562 cites W2137943169 @default.
- W2092505562 cites W2138563960 @default.
- W2092505562 cites W2140292029 @default.
- W2092505562 cites W2147057682 @default.
- W2092505562 cites W2149799872 @default.
- W2092505562 cites W2155918029 @default.
- W2092505562 cites W2162261737 @default.
- W2092505562 cites W2169655990 @default.
- W2092505562 doi "https://doi.org/10.1002/1097-0061(20010130)18:2<163::aid-yea659>3.0.co;2-#" @default.
- W2092505562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11169758" @default.
- W2092505562 hasPublicationYear "2000" @default.
- W2092505562 type Work @default.
- W2092505562 sameAs 2092505562 @default.
- W2092505562 citedByCount "19" @default.
- W2092505562 countsByYear W20925055622013 @default.
- W2092505562 countsByYear W20925055622014 @default.
- W2092505562 countsByYear W20925055622015 @default.
- W2092505562 countsByYear W20925055622017 @default.
- W2092505562 countsByYear W20925055622018 @default.
- W2092505562 countsByYear W20925055622021 @default.
- W2092505562 crossrefType "journal-article" @default.
- W2092505562 hasAuthorship W2092505562A5009649673 @default.
- W2092505562 hasAuthorship W2092505562A5021095726 @default.
- W2092505562 hasAuthorship W2092505562A5049417333 @default.
- W2092505562 hasAuthorship W2092505562A5058279698 @default.
- W2092505562 hasConcept C116834253 @default.
- W2092505562 hasConcept C119062480 @default.
- W2092505562 hasConcept C1491633281 @default.
- W2092505562 hasConcept C2779222958 @default.
- W2092505562 hasConcept C2780212709 @default.
- W2092505562 hasConcept C2780224938 @default.
- W2092505562 hasConcept C2781373781 @default.
- W2092505562 hasConcept C55493867 @default.
- W2092505562 hasConcept C59822182 @default.
- W2092505562 hasConcept C79879829 @default.
- W2092505562 hasConcept C86803240 @default.
- W2092505562 hasConcept C95444343 @default.
- W2092505562 hasConceptScore W2092505562C116834253 @default.
- W2092505562 hasConceptScore W2092505562C119062480 @default.
- W2092505562 hasConceptScore W2092505562C1491633281 @default.