Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092505622> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2092505622 endingPage "206" @default.
- W2092505622 startingPage "199" @default.
- W2092505622 abstract "The conditions for induction of B-cell inducing factor (BIF) by human peripheral blood T cells was investigated. BIF was assayed by induction of immunoglobulin secreting cells (ISC) in peripheral blood B (non-T) cells stimulated with Staphylococcus aureus bacteria strain Cowan I (Sac), and in the IgM cell line SKW6.4. Maximum BIF production occurred with high concentrations of the T-cell mitogens phytohemagglutinin, concanavalin A, and PWM. Dexamethasone (Dex) also induced BIF production in T cells at 10−5 to 10−7M. At 10−5 and 10−6M Dex, the T-cell supernatants had to be dialyzed before testing because Dex alone stimulated variable levels of ISC in both test B-cell assays. Dex did not enhance BIF production by T cells that were optimally stimulated by lectin. BIF levels were maximum by Day 2 of T-cell cultures and remained high at Days 3 and 4. In contrast, IL-2 reached a peak at Day 1 and declined drastically by Day 4. We previously showed that IL-2 at less than 100 U/ml did not induce ISC in B cells and did not alter ISC induction by BIF. Dex did not induce IL-2 production and inhibited IL-2 production induced by Con A, in contrast to the promoting effects of Dex on BIF production, providing further evidence for the independence of BIF and IL-2 production and B-cell stimulation." @default.
- W2092505622 created "2016-06-24" @default.
- W2092505622 creator A5019763111 @default.
- W2092505622 creator A5048387840 @default.
- W2092505622 creator A5053871036 @default.
- W2092505622 date "1986-11-01" @default.
- W2092505622 modified "2023-09-26" @default.
- W2092505622 title "Independent regulation of B-cell inducing factor and IL-2 production by T lymphocytes, and direct and indirect promotion of immunoglobulin secretion by glucocorticosteroid" @default.
- W2092505622 cites W1503659276 @default.
- W2092505622 cites W1524978777 @default.
- W2092505622 cites W1531906037 @default.
- W2092505622 cites W1602791090 @default.
- W2092505622 cites W1659719165 @default.
- W2092505622 cites W1906216555 @default.
- W2092505622 cites W1917477049 @default.
- W2092505622 cites W2015808576 @default.
- W2092505622 cites W2016890634 @default.
- W2092505622 cites W2083628027 @default.
- W2092505622 cites W2087487356 @default.
- W2092505622 cites W2091505207 @default.
- W2092505622 cites W2096623937 @default.
- W2092505622 cites W2098415367 @default.
- W2092505622 cites W2104196887 @default.
- W2092505622 cites W2130859575 @default.
- W2092505622 cites W2153652726 @default.
- W2092505622 cites W80617079 @default.
- W2092505622 doi "https://doi.org/10.1016/0008-8749(86)90081-x" @default.
- W2092505622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3492284" @default.
- W2092505622 hasPublicationYear "1986" @default.
- W2092505622 type Work @default.
- W2092505622 sameAs 2092505622 @default.
- W2092505622 citedByCount "2" @default.
- W2092505622 crossrefType "journal-article" @default.
- W2092505622 hasAuthorship W2092505622A5019763111 @default.
- W2092505622 hasAuthorship W2092505622A5048387840 @default.
- W2092505622 hasAuthorship W2092505622A5053871036 @default.
- W2092505622 hasConcept C126322002 @default.
- W2092505622 hasConcept C134018914 @default.
- W2092505622 hasConcept C153911025 @default.
- W2092505622 hasConcept C159654299 @default.
- W2092505622 hasConcept C19869320 @default.
- W2092505622 hasConcept C202751555 @default.
- W2092505622 hasConcept C203014093 @default.
- W2092505622 hasConcept C24998067 @default.
- W2092505622 hasConcept C2776090121 @default.
- W2092505622 hasConcept C2778453870 @default.
- W2092505622 hasConcept C55493867 @default.
- W2092505622 hasConcept C71924100 @default.
- W2092505622 hasConcept C86803240 @default.
- W2092505622 hasConcept C8891405 @default.
- W2092505622 hasConceptScore W2092505622C126322002 @default.
- W2092505622 hasConceptScore W2092505622C134018914 @default.
- W2092505622 hasConceptScore W2092505622C153911025 @default.
- W2092505622 hasConceptScore W2092505622C159654299 @default.
- W2092505622 hasConceptScore W2092505622C19869320 @default.
- W2092505622 hasConceptScore W2092505622C202751555 @default.
- W2092505622 hasConceptScore W2092505622C203014093 @default.
- W2092505622 hasConceptScore W2092505622C24998067 @default.
- W2092505622 hasConceptScore W2092505622C2776090121 @default.
- W2092505622 hasConceptScore W2092505622C2778453870 @default.
- W2092505622 hasConceptScore W2092505622C55493867 @default.
- W2092505622 hasConceptScore W2092505622C71924100 @default.
- W2092505622 hasConceptScore W2092505622C86803240 @default.
- W2092505622 hasConceptScore W2092505622C8891405 @default.
- W2092505622 hasIssue "1" @default.
- W2092505622 hasLocation W20925056221 @default.
- W2092505622 hasLocation W20925056222 @default.
- W2092505622 hasOpenAccess W2092505622 @default.
- W2092505622 hasPrimaryLocation W20925056221 @default.
- W2092505622 hasRelatedWork W1984619393 @default.
- W2092505622 hasRelatedWork W2034768996 @default.
- W2092505622 hasRelatedWork W2060618991 @default.
- W2092505622 hasRelatedWork W2064416809 @default.
- W2092505622 hasRelatedWork W2072396112 @default.
- W2092505622 hasRelatedWork W2111773719 @default.
- W2092505622 hasRelatedWork W2146937064 @default.
- W2092505622 hasRelatedWork W2163700154 @default.
- W2092505622 hasRelatedWork W4233524856 @default.
- W2092505622 hasRelatedWork W4240797670 @default.
- W2092505622 hasVolume "103" @default.
- W2092505622 isParatext "false" @default.
- W2092505622 isRetracted "false" @default.
- W2092505622 magId "2092505622" @default.
- W2092505622 workType "article" @default.