FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092508028> ?p ?o ?g. }

• W2092508028 endingPage "94" @default.
• W2092508028 startingPage "88" @default.
• W2092508028 abstract "Animal models have confirmed high efficiency of combined tocolytic treatment in preterm labour. In humans, the recommended doses of tocolytic drugs prolong pregnancy in threatened preterm labour. The aim of the study was to evaluate the inhibitory effect of dual combinations of atosiban, nifedipine and celecoxib on human myometrial strips contractility on the in vitro model of preterm labour. Two groups of patients who delivered by cesarean section were involved in the study: 36 patients who delivered preterm between the 24th and 34th week of pregnancy and 40 patients who delivered at term. Myometrial samples were obtained from the lower uterine segment during cesarean sections. Contractile activity was recorded with digital software for each drug combination: atosiban/nifedipine; atosiban/celecoxib, nifedipine/celecoxib. Tocolytic efficiency of the drug combinations was assessed using IC50 parameter – a molar drug concentration inhibiting 50% of contractility. The atosiban/nifedipine combination has shown additive tocolytic effect on myometrial strips contractility in preterm and term patients. The other combinations: atosiban/celecoxib and nifedipine/celecoxib presented only antagonistic effects in both studied groups. The effect of the combined therapy on human myometrial contractility presented in the study could be a base for further in vivo clinical trials." @default.
• W2092508028 created "2016-06-24" @default.
• W2092508028 creator A5009181512 @default.
• W2092508028 creator A5017092207 @default.
• W2092508028 creator A5042423220 @default.
• W2092508028 creator A5088004344 @default.
• W2092508028 date "2011-06-01" @default.
• W2092508028 modified "2023-10-18" @default.
• W2092508028 title "The effect of combined tocolysis on in vitro uterine contractility in preterm labour" @default.
• W2092508028 cites W13504714 @default.
• W2092508028 cites W1966780028 @default.
• W2092508028 cites W1967339035 @default.
• W2092508028 cites W1968620373 @default.
• W2092508028 cites W1970478529 @default.
• W2092508028 cites W1978869614 @default.
• W2092508028 cites W1988501400 @default.
• W2092508028 cites W1993866499 @default.
• W2092508028 cites W1999186303 @default.
• W2092508028 cites W2019078592 @default.
• W2092508028 cites W2027994995 @default.
• W2092508028 cites W2036135301 @default.
• W2092508028 cites W2044148882 @default.
• W2092508028 cites W2046856862 @default.
• W2092508028 cites W2054837981 @default.
• W2092508028 cites W2063843904 @default.
• W2092508028 cites W2069044207 @default.
• W2092508028 cites W2071403047 @default.
• W2092508028 cites W2082300882 @default.
• W2092508028 cites W2113461843 @default.
• W2092508028 cites W2120273877 @default.
• W2092508028 cites W2122212460 @default.
• W2092508028 cites W2132133945 @default.
• W2092508028 cites W2136174167 @default.
• W2092508028 cites W2142998361 @default.
• W2092508028 cites W2150682993 @default.
• W2092508028 cites W4211135592 @default.
• W2092508028 doi "https://doi.org/10.2478/v10039-011-0019-x" @default.
• W2092508028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21555303" @default.
• W2092508028 hasPublicationYear "2011" @default.
• W2092508028 type Work @default.
• W2092508028 sameAs 2092508028 @default.
• W2092508028 citedByCount "18" @default.
• W2092508028 countsByYear W20925080282012 @default.
• W2092508028 countsByYear W20925080282013 @default.
• W2092508028 countsByYear W20925080282016 @default.
• W2092508028 countsByYear W20925080282017 @default.
• W2092508028 countsByYear W20925080282018 @default.
• W2092508028 countsByYear W20925080282019 @default.
• W2092508028 countsByYear W20925080282021 @default.
• W2092508028 countsByYear W20925080282022 @default.
• W2092508028 countsByYear W20925080282023 @default.
• W2092508028 crossrefType "journal-article" @default.
• W2092508028 hasAuthorship W2092508028A5009181512 @default.
• W2092508028 hasAuthorship W2092508028A5017092207 @default.
• W2092508028 hasAuthorship W2092508028A5042423220 @default.
• W2092508028 hasAuthorship W2092508028A5088004344 @default.
• W2092508028 hasConcept C126322002 @default.
• W2092508028 hasConcept C172680121 @default.
• W2092508028 hasConcept C2776467144 @default.
• W2092508028 hasConcept C2776561140 @default.
• W2092508028 hasConcept C2776766599 @default.
• W2092508028 hasConcept C2779066055 @default.
• W2092508028 hasConcept C2779066535 @default.
• W2092508028 hasConcept C2779234561 @default.
• W2092508028 hasConcept C2780931799 @default.
• W2092508028 hasConcept C2908881489 @default.
• W2092508028 hasConcept C3019152611 @default.
• W2092508028 hasConcept C39133596 @default.
• W2092508028 hasConcept C42219234 @default.
• W2092508028 hasConcept C46973012 @default.
• W2092508028 hasConcept C519063684 @default.
• W2092508028 hasConcept C54355233 @default.
• W2092508028 hasConcept C71924100 @default.
• W2092508028 hasConcept C86803240 @default.
• W2092508028 hasConcept C98274493 @default.
• W2092508028 hasConceptScore W2092508028C126322002 @default.
• W2092508028 hasConceptScore W2092508028C172680121 @default.
• W2092508028 hasConceptScore W2092508028C2776467144 @default.
• W2092508028 hasConceptScore W2092508028C2776561140 @default.
• W2092508028 hasConceptScore W2092508028C2776766599 @default.
• W2092508028 hasConceptScore W2092508028C2779066055 @default.
• W2092508028 hasConceptScore W2092508028C2779066535 @default.
• W2092508028 hasConceptScore W2092508028C2779234561 @default.
• W2092508028 hasConceptScore W2092508028C2780931799 @default.
• W2092508028 hasConceptScore W2092508028C2908881489 @default.
• W2092508028 hasConceptScore W2092508028C3019152611 @default.
• W2092508028 hasConceptScore W2092508028C39133596 @default.
• W2092508028 hasConceptScore W2092508028C42219234 @default.
• W2092508028 hasConceptScore W2092508028C46973012 @default.
• W2092508028 hasConceptScore W2092508028C519063684 @default.
• W2092508028 hasConceptScore W2092508028C54355233 @default.
• W2092508028 hasConceptScore W2092508028C71924100 @default.
• W2092508028 hasConceptScore W2092508028C86803240 @default.
• W2092508028 hasConceptScore W2092508028C98274493 @default.
• W2092508028 hasIssue "1" @default.
• W2092508028 hasLocation W20925080281 @default.
• W2092508028 hasLocation W20925080282 @default.
• W2092508028 hasOpenAccess W2092508028 @default.

• next