FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092509626> ?p ?o ?g. }

• W2092509626 endingPage "613" @default.
• W2092509626 startingPage "603" @default.
• W2092509626 abstract "The reduction potentials of 22 yeast cytochrome c peroxidase (CcP) mutants were determined at pH 7.0 in order to determine the effect of both heme pocket and surface mutations on the Fe(III)/Fe(II) redox couple of CcP, as well as to determine the range in redox potentials that could be obtained through point mutations in the enzyme. Spectroscopic properties of the Fe(III) and Fe(II) forms of the mutant enzymes are also reported. The mutations include variants in the distal and proximal heme pockets as well as on the enzyme surface and involve single, double, and triple point mutations. A spectrochemical redox titration technique used in this study gave an E0′ value of −189 mV for yeast CcP compared to a previously reported value of −194 mV determined by potentiometry [C.W. Conroy, P. Tyma, P.H. Daum, J.E. Erman, Biochim. Biophys. Acta 537 (1978) 62–69]. Both positive and negative shifts in the reduction potential from that of the wild-type enzyme were observed, spanning a range of 113 mV. The His-52 → Asn mutation gave the most negative potential, −259 mV, while a triple mutant in which the three distal pocket residues, Arg-48, Trp-51, and His-52, were all converted to leucine residues gave the most positive potential, −146 mV." @default.
• W2092509626 created "2016-06-24" @default.
• W2092509626 creator A5019356414 @default.
• W2092509626 creator A5049376567 @default.
• W2092509626 creator A5087172093 @default.
• W2092509626 date "2007-04-01" @default.
• W2092509626 modified "2023-10-14" @default.
• W2092509626 title "Effect of active site and surface mutations on the reduction potential of yeast cytochrome c peroxidase and spectroscopic properties of the oxidized and reduced enzyme" @default.
• W2092509626 cites W1500539090 @default.
• W2092509626 cites W1507928509 @default.
• W2092509626 cites W1535104931 @default.
• W2092509626 cites W1586433464 @default.
• W2092509626 cites W1650427240 @default.
• W2092509626 cites W1663570012 @default.
• W2092509626 cites W1821837169 @default.
• W2092509626 cites W1866116049 @default.
• W2092509626 cites W1964088665 @default.
• W2092509626 cites W1965059091 @default.
• W2092509626 cites W1967683552 @default.
• W2092509626 cites W1970231630 @default.
• W2092509626 cites W1981974511 @default.
• W2092509626 cites W1990457244 @default.
• W2092509626 cites W1992823853 @default.
• W2092509626 cites W2007110429 @default.
• W2092509626 cites W2007408386 @default.
• W2092509626 cites W2017147627 @default.
• W2092509626 cites W2022798135 @default.
• W2092509626 cites W2023042894 @default.
• W2092509626 cites W2023913135 @default.
• W2092509626 cites W2026182346 @default.
• W2092509626 cites W2032286237 @default.
• W2092509626 cites W2045374740 @default.
• W2092509626 cites W2048459982 @default.
• W2092509626 cites W2051029337 @default.
• W2092509626 cites W2057959947 @default.
• W2092509626 cites W2062962307 @default.
• W2092509626 cites W2062979963 @default.
• W2092509626 cites W2063368322 @default.
• W2092509626 cites W2069599139 @default.
• W2092509626 cites W2069631900 @default.
• W2092509626 cites W2070385082 @default.
• W2092509626 cites W2072679497 @default.
• W2092509626 cites W2073178248 @default.
• W2092509626 cites W2077543622 @default.
• W2092509626 cites W2081945699 @default.
• W2092509626 cites W2091882732 @default.
• W2092509626 cites W2401554756 @default.
• W2092509626 cites W4293258013 @default.
• W2092509626 cites W45126112 @default.
• W2092509626 doi "https://doi.org/10.1016/j.jinorgbio.2006.12.006" @default.
• W2092509626 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1945249" @default.
• W2092509626 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17275914" @default.
• W2092509626 hasPublicationYear "2007" @default.
• W2092509626 type Work @default.
• W2092509626 sameAs 2092509626 @default.
• W2092509626 citedByCount "16" @default.
• W2092509626 countsByYear W20925096262012 @default.
• W2092509626 countsByYear W20925096262015 @default.
• W2092509626 countsByYear W20925096262020 @default.
• W2092509626 countsByYear W20925096262021 @default.
• W2092509626 crossrefType "journal-article" @default.
• W2092509626 hasAuthorship W2092509626A5019356414 @default.
• W2092509626 hasAuthorship W2092509626A5049376567 @default.
• W2092509626 hasAuthorship W2092509626A5087172093 @default.
• W2092509626 hasBestOaLocation W20925096262 @default.
• W2092509626 hasConcept C104317684 @default.
• W2092509626 hasConcept C133166286 @default.
• W2092509626 hasConcept C143065580 @default.
• W2092509626 hasConcept C162008176 @default.
• W2092509626 hasConcept C176944494 @default.
• W2092509626 hasConcept C179104552 @default.
• W2092509626 hasConcept C181199279 @default.
• W2092509626 hasConcept C185592680 @default.
• W2092509626 hasConcept C207583985 @default.
• W2092509626 hasConcept C2776217839 @default.
• W2092509626 hasConcept C2777676563 @default.
• W2092509626 hasConcept C2779222958 @default.
• W2092509626 hasConcept C2780768313 @default.
• W2092509626 hasConcept C501734568 @default.
• W2092509626 hasConcept C55493867 @default.
• W2092509626 hasConcept C55904794 @default.
• W2092509626 hasConcept C71240020 @default.
• W2092509626 hasConcept C8010536 @default.
• W2092509626 hasConceptScore W2092509626C104317684 @default.
• W2092509626 hasConceptScore W2092509626C133166286 @default.
• W2092509626 hasConceptScore W2092509626C143065580 @default.
• W2092509626 hasConceptScore W2092509626C162008176 @default.
• W2092509626 hasConceptScore W2092509626C176944494 @default.
• W2092509626 hasConceptScore W2092509626C179104552 @default.
• W2092509626 hasConceptScore W2092509626C181199279 @default.
• W2092509626 hasConceptScore W2092509626C185592680 @default.
• W2092509626 hasConceptScore W2092509626C207583985 @default.
• W2092509626 hasConceptScore W2092509626C2776217839 @default.
• W2092509626 hasConceptScore W2092509626C2777676563 @default.
• W2092509626 hasConceptScore W2092509626C2779222958 @default.
• W2092509626 hasConceptScore W2092509626C2780768313 @default.
• W2092509626 hasConceptScore W2092509626C501734568 @default.
• W2092509626 hasConceptScore W2092509626C55493867 @default.

• next