FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092580379> ?p ?o ?g. }

• W2092580379 endingPage "39" @default.
• W2092580379 startingPage "29" @default.
• W2092580379 abstract "Fluorescence Correlation Spectroscopy (FCS) is used to study the interaction of a recently designed antimicrobial peptide, called V4, with LPS and lipids of varying head and tail groups. V4 is designed based on a known amphipathic cationic pattern BHPHB (B: basic; H: hydrophobic; P: polar residue, respectively) and shows a good combination of high antimicrobial activity, low cytotoxic activity and low hemolytic activity. It is shown that V4 has high binding affinity for LPS, which is the major component of the outer membrane of Gram-negative bacteria, and shows selectivity for negatively charged lipids in contrast to zwitterionic lipids at a low peptide/lipid ratio. At high peptide/lipid ratio, V4 can permeabilize vesicles composed of negatively charged lipids and eventually cause vesicle fusion. The identification of the amphipathic cationic pattern as the mediator of selectivity and antimicrobial activity could be a first step in the rational design of better antimicrobial peptides." @default.
• W2092580379 created "2016-06-24" @default.
• W2092580379 creator A5014356088 @default.
• W2092580379 creator A5016756488 @default.
• W2092580379 creator A5062156792 @default.
• W2092580379 creator A5071335197 @default.
• W2092580379 date "2005-10-01" @default.
• W2092580379 modified "2023-10-18" @default.
• W2092580379 title "Investigation of a novel artificial antimicrobial peptide by fluorescence correlation spectroscopy: An amphipathic cationic pattern is sufficient for selective binding to bacterial type membranes and antimicrobial activity" @default.
• W2092580379 cites W1483409860 @default.
• W2092580379 cites W1556677948 @default.
• W2092580379 cites W1938224903 @default.
• W2092580379 cites W1967506638 @default.
• W2092580379 cites W1968713178 @default.
• W2092580379 cites W1970621669 @default.
• W2092580379 cites W1981765336 @default.
• W2092580379 cites W1983521156 @default.
• W2092580379 cites W1986752048 @default.
• W2092580379 cites W1995272676 @default.
• W2092580379 cites W2003897459 @default.
• W2092580379 cites W2011187994 @default.
• W2092580379 cites W2013896356 @default.
• W2092580379 cites W2015223037 @default.
• W2092580379 cites W2020447495 @default.
• W2092580379 cites W2020790969 @default.
• W2092580379 cites W2022577580 @default.
• W2092580379 cites W2031143043 @default.
• W2092580379 cites W2031562047 @default.
• W2092580379 cites W2043930412 @default.
• W2092580379 cites W2061466767 @default.
• W2092580379 cites W2061948699 @default.
• W2092580379 cites W2062515534 @default.
• W2092580379 cites W2064493683 @default.
• W2092580379 cites W2064757943 @default.
• W2092580379 cites W2079468421 @default.
• W2092580379 cites W2082844643 @default.
• W2092580379 cites W2084037807 @default.
• W2092580379 cites W2085611814 @default.
• W2092580379 cites W2089833507 @default.
• W2092580379 cites W2091874747 @default.
• W2092580379 cites W2097548272 @default.
• W2092580379 cites W2110244050 @default.
• W2092580379 cites W2134867392 @default.
• W2092580379 cites W2137978643 @default.
• W2092580379 cites W2145344160 @default.
• W2092580379 cites W2158789628 @default.
• W2092580379 cites W2163930707 @default.
• W2092580379 doi "https://doi.org/10.1016/j.bbamem.2005.08.005" @default.
• W2092580379 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16168384" @default.
• W2092580379 hasPublicationYear "2005" @default.
• W2092580379 type Work @default.
• W2092580379 sameAs 2092580379 @default.
• W2092580379 citedByCount "18" @default.
• W2092580379 countsByYear W20925803792014 @default.
• W2092580379 countsByYear W20925803792017 @default.
• W2092580379 countsByYear W20925803792018 @default.
• W2092580379 countsByYear W20925803792019 @default.
• W2092580379 countsByYear W20925803792020 @default.
• W2092580379 countsByYear W20925803792021 @default.
• W2092580379 countsByYear W20925803792023 @default.
• W2092580379 crossrefType "journal-article" @default.
• W2092580379 hasAuthorship W2092580379A5014356088 @default.
• W2092580379 hasAuthorship W2092580379A5016756488 @default.
• W2092580379 hasAuthorship W2092580379A5062156792 @default.
• W2092580379 hasAuthorship W2092580379A5071335197 @default.
• W2092580379 hasBestOaLocation W20925803791 @default.
• W2092580379 hasConcept C107565407 @default.
• W2092580379 hasConcept C121332964 @default.
• W2092580379 hasConcept C12554922 @default.
• W2092580379 hasConcept C130316041 @default.
• W2092580379 hasConcept C158711907 @default.
• W2092580379 hasConcept C15920480 @default.
• W2092580379 hasConcept C178790620 @default.
• W2092580379 hasConcept C183882617 @default.
• W2092580379 hasConcept C185592680 @default.
• W2092580379 hasConcept C21951064 @default.
• W2092580379 hasConcept C2779281246 @default.
• W2092580379 hasConcept C41625074 @default.
• W2092580379 hasConcept C4937899 @default.
• W2092580379 hasConcept C521977710 @default.
• W2092580379 hasConcept C540938839 @default.
• W2092580379 hasConcept C55493867 @default.
• W2092580379 hasConcept C62520636 @default.
• W2092580379 hasConcept C67407626 @default.
• W2092580379 hasConcept C86803240 @default.
• W2092580379 hasConcept C91881484 @default.
• W2092580379 hasConceptScore W2092580379C107565407 @default.
• W2092580379 hasConceptScore W2092580379C121332964 @default.
• W2092580379 hasConceptScore W2092580379C12554922 @default.
• W2092580379 hasConceptScore W2092580379C130316041 @default.
• W2092580379 hasConceptScore W2092580379C158711907 @default.
• W2092580379 hasConceptScore W2092580379C15920480 @default.
• W2092580379 hasConceptScore W2092580379C178790620 @default.
• W2092580379 hasConceptScore W2092580379C183882617 @default.
• W2092580379 hasConceptScore W2092580379C185592680 @default.
• W2092580379 hasConceptScore W2092580379C21951064 @default.
• W2092580379 hasConceptScore W2092580379C2779281246 @default.
• W2092580379 hasConceptScore W2092580379C41625074 @default.

• next